頁籤選單縮合
題名 | Antivenin-related Serum Sickness=抗蛇毒血清引起血清病 |
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作者姓名(中文) | 黃錦源; 洪東榮; 陳維恭; | 書刊名 | Journal of the Chinese Medical Association |
卷期 | 73:10 2010.10[民99.10] |
頁次 | 頁540-542+CA96 |
分類號 | 418.87 |
關鍵詞 | 抗蛇毒血清; 血清病; 毒蛇咬傷; Antivenin; Serum sickness; Snakebite; |
語文 | 英文(English) |
英文摘要 | Serum sickness is a type III hypersensitivity reaction that occurs due to the deposition of excessive circulating immune complexes in patients treated with foreign proteins or haptens. Serum sickness induced by antivenin for snakebites has been frequently reported in the USA, but not in Taiwan. This difference may be due to the efficacy and dosage of antivenins administered to treat snakebites in Taiwan. We report a case presenting with serum sickness after receiving a total of 20 vials of polyvalent antivenin therapy for the treatment of snakebite. A 59-year-old male suffered from fever, headaches, polyarthritis, and diffused skin rash approximately 10 days after administration of the antivenin. The large dose of antivenin administered in this case might have been the cause of the development of serum sickness. Physicians should be aware of the potential for serum sickness in cases of large-dose antivenin use. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。