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頁籤選單縮合
題名 | Surgical Outcomes in Resected Non-small Cell Lung Cancer <= 1 cm in Diameter=小於一公分非小細胞肺癌病人之手術預後 |
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作者 | 王秉彥; 洪榮志; 鄭文睿; 許文虎; 謝致政; 黃敏雄; 黃炳勳; 劉榮森; 吳玉琮; Wang, Bing-yen; Hung, Jung-jyh; Jeng, Wen-juei; Hsu, Wen-hu; Hsieh, Chih-cheng; Huang, Min-hsiung; Huang, Biing-shiun; Liu, Jung-sen; Wu, Yu-chung; |
期刊 | Journal of the Chinese Medical Association |
出版日期 | 20100600 |
卷期 | 73:6 2010.06[民99.06] |
頁次 | 頁308-313+CA54 |
語文 | eng |
關鍵詞 | 非小細胞肺癌; 小於一公分; 存活; 預測因子; 亞肺葉切除; Non-small cell lung cancer; Predictor; Subcentimeter; Sublobar resection; Survival; |
英文摘要 | Background: The goal of this study was to investigate the prognostic factors and patterns of recurrence in patients with resected non-small cell lung cancer (NSCLC) ≤ 1 cm in diameter. Methods: We conducted a retrospective review of the clinicopathological characteristics of 71 patients with NSCLC ≤ 1 cm in diameter in Taipei Veterans General Hospital between 1982 and 2007. Overall survival and its predictors were analyzed. Results: Median follow-up time of the 71 patients was 33.3 months. Complete resection was performed in 68 patients (95.8%) with stage I disease. The 5- and 10-year overall survival rates of patients who underwent complete resections were 81.7% and 44.9%, respectively. There was tumor recurrence in 6 (8.8%) of these 68 patients. Five (9.3%) of 54 patients who underwent standard resection experienced tumor recurrence, but only 1 (7.1%) of 14 patients who received sublobar resection had recurrent disease. The difference was not statistically significant (p = 0.569). Multivariate analysis revealed that sublobar resection (hazard ratio, 5.00; 95% confidence interval, 1.28–20.00; p = 0.020) was a significant predictor for worse overall survival. Conclusion: Survival in patients with NSCLC ≤ 1 cm in diameter is satisfactory. Sublobar resection, performed in patients unfit for standard resection, is a poor prognostic factor for overall survival. |
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