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| 題 名 | Early-Onset Stroke in a Patient with Nasopharyngeal Cancer Associated with Protein C Deficiency |
|---|---|
| 作 者 | Chiu, Ya-ning; Wang, Tyng-guey; Chang, Chein-wei; | 書刊名 | Journal of the Formosan Medical Association |
| 卷 期 | 108:7 2009.07[民98.07] |
| 頁 次 | 頁592-594 |
| 分類號 | 416.879 |
| 關鍵詞 | Carotid stenosis; Nasopharyngeal cancer; Protein C deficiency; Radiotherapy; Stroke; |
| 語 文 | 英文(English) |
| 英文摘要 | We report a 47-year-old male stroke patient with nasopharyngeal cancer (NPC) and protein C deficiency. The patient was diagnosed with NPC and received a complete course of radiotherapy. Infarction stroke occurred 28 months after radiotherapy and magnetic resonance imaging of the brain confirmed the diagnosis. Carotid duplex sonography showed 50–79% stenosis in his left internal carotid artery. Coagulation profiles indicated protein C deficiency. After medical treatment and rehabilitation, the patient regained the ability to walk and he could perform most of his daily activities. Radiotherapy-induced carotid stenosis is an exacerbating feature of stroke in patients with protein C deficiency. We suggest early carotid duplex sonography and survey of the coagulation profile to prevent a stroke in patients with NPC. |
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