頁籤選單縮合
| 題 名 | Lung Maturation: The Survival Miracle of Very Low Birth Weight Infants |
|---|---|
| 作 者 | Jobe, Alan H.; | 書刊名 | Pediatrics and Neonatology |
| 卷 期 | 51:1 2010.02[民99.02] |
| 頁 次 | 頁7-13 |
| 分類號 | 417.5171 |
| 關鍵詞 | Lung maturation; Prematurity; Prenatal corticosteroids; Respiratory distress syndrome; Surfactant; |
| 語 文 | 英文(English) |
| 英文摘要 | The increased survival of very preterm infants is generally attributed to improved care strategies. This review develops the thesis that the features of abnormal pregnancies responsible for very preterm deliveries also provide an explanation of why very preterm infants often survive. A normal fetus born at 24 weeks is very unlikely to survive. However, pregnancies that result in deliveries at 24 weeks are generally highly abnormal, and may have been so for prolonged periods prior to the preterm deliveries. Inflammatory or vascular developmental abnormalities resulting in very preterm birth can alter fetal development in such a way that organ system maturation is induced. This is supported clinically by the relative lack of very preterm infants with respiratory distress syndrome. Interventions such as antenatal corticosteroid treatment and postnatal surfactant treatment for infants with respiratory distress syndrome and gentle ventilation strategies maximize fetal adaptations to the abnormal fetal environment and improve outcomes. |
本系統中英文摘要資訊取自各篇刊載內容。