頁籤選單縮合
題名 | Clinical Presentations, Prognostic Factors, and Mortality in Patients with Aeromonas Sobria Complex Bacteremia in a Teaching Hospital: A 5-year Experience |
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作者姓名(外文) | Wang, Chien-yu; Chi, Chih-yu; Ho, Mao-wang; Ho, Cheng-mao; Lin, Po-chang; Wang, Chen-hsien; | 書刊名 | 微免與感染雜誌 |
卷期 | 42:6 2009.12[民98.12] |
頁次 | 頁510-515 |
分類號 | 415.27 |
關鍵詞 | Aeromonas sobria; Bacteremia; Liver cirrhosis; Neoplasms; Taiwan; |
語文 | 英文(English) |
英文摘要 | Background and purpose: Bacteremia due to Aeromonas sobria complex is an uncommon clinical presentation, associated with a high mortality rate. This retrospective study reviewed the clinical manifestations and prognostic factors of A. sobria complex bacteremia. Methods: From September 2001 to August 2006, all adult patients with A. sobria complex bacteremia treated at a tertiary medical center in Taiwan were included. Antibiotic susceptibility was tested by disc diffusion method. Results: Of 33 patients with A. sobria complex bacteremia, 66.7% were men and 72.0% were older than 50 years. Most patients (72.7%) had community-acquired infection. The commonest associated conditions were liver cirrhosis (42.4%) and neoplasm (30.3%). With the exception of diarrhea, the clinical manifestations were similar to those of other Aeromonas spp. Secondary bacteremia occurred in 51.5% of patients, most of whom had either biliary tract infection (47%) or peritonitis (23.5%) as the major infection focus. Monomicrobial bacteremia was recorded in 23 patients. All isolates were susceptible to gentamicin, amikacin, ceftazidime, cefepime, and ciprofloxacin; 90.9% were susceptible to aztreonam and piperacillin-tazobactam, 87.9% to imipenem, and 78.8% to trimethoprim-sulfamethoxazole. The mortality rate was 39.4% and nearly 50% of deaths occurred within 96 h of admission. Hypotension, impaired renal function, and liver cirrhosis were significantly associated with a high mortality rate. Conclusions: A. sobria complex bacteremia usually occurs in patients with liver cirrhosis or neoplasm. In patients with A. sobria complex bacteremia, a secondary infection focus should be considered. Adequate antibiotics should be given early, especially to patients with hypotension and impaired renal function. |
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