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題 名 | High-frequency Somatosensory Evoked Potentials of Normal Subjects=正常人的高頻體感覺誘發電位 |
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作 者 | 林家億; 葉彥琪; 賴冠霖; 陳仁澤; 王署君; 林永煬; 廖光淦; | 書刊名 | Acta Neurologica Taiwanica |
卷 期 | 18:3 2009.09[民98.09] |
頁 次 | 頁180-186 |
分類號 | 415.9 |
關鍵詞 | 高頻; 體感覺誘發電位; 神經; Somatosensory evoked potential; High-frequency oscillation; Median nerve; |
語 文 | 英文(English) |
英文摘要 | Background: We investigated the characteristics and correlates of high-frequency oscillations (HFOs) of somatosensory evoked potentials (SEPs). Methods: Subjects were 26 healthy volunteers. SEP was recorded from the hand sensory area contralateral to the median nerve stimulated at the wrist. HFOs were obtained by digitally filtering raw SEPs from 500 to 1000 Hz, and their amplitudes and area-under-curve, duration, and number of negative peaks were measured. We also measured amplitudes of the N20 onset-peak (N20o-p), and N20 peak-P25 peak (N20p-P25p). Results: In normal subjects, several oscillation potentials were observed at the latency of 0 to 10 ms after the onset of N20. The mean number of negative peaks of total HFOs was 6.96 Ų 1.20 (early phase 3.36 Ų 0.62; late phase 3.60 Ų 1.14). The mean maximal amplitude of total HFOs was 0.16 Ų 0.07 µV (early phase 0.14 Ų 0.05 µV; late phase 0.15 Ų 0.07 µV). The mean duration of total HFOs was 10.19 Ų 1.98 ms (early phase 4.89 Ų 1.04 ms; late phase 5.31 Ų 1.95 ms). The mean area of total HFOs was 567.54 Ų 227.86 µVąms (early phase 268.46 Ų 98.40 µVąms; late phase 299.08 Ų 183.44 µVąms). The amplitude ratio was 7.30 Ų 3.32% of HFOearly/N20o-p, 3.19 Ų 1.55% of HFOlate/N20-P25, and 3.54 Ų 1.84% of HFOtotal/N20p-P25. During the test, the amplitude of HFO was significantly reduced by drowsiness. Conclusions: In waking subjects, a burst of low-amplitude HFO can be extracted from the N20. |
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