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題名 | Reversible Posterior Leukoencephalopathy Syndrome Caused by Blood Transfusion : A Case Report=輸血導致之可逆性後大腦白質病變:一病例報告 |
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作者 | 黃永銓; 蔡佩霖; 葉建宏; 陳威宏; Huang, Yung-chuan; Tsai, Pei-lin; Yeh, Jiann-horng; Chen, Wei-hung; |
期刊 | Acta Neurologica Taiwanica |
出版日期 | 20081200 |
卷期 | 17:4 2008.12[民97.12] |
頁次 | 頁258-262 |
分類號 | 415.835 |
語文 | eng |
關鍵詞 | 輸血; 大腦; 可逆性後大腦白質病變症候群; Posterior leukoencephalopathy; Hyperperfusion syndrome; Transfusion complication; Cerebral autoregulation; |
英文摘要 | This is a case report of a 32-year-old woman with chronic severe anemia who developed headaches and seizures 5 days after receiving a blood transfusion of eight units (1600 ml) of packed red blood cells. Magnetic resonance imaging indicated vasogenic edematous lesions bilaterally over the occipital lobes that were consistent with reversible posterior leukoencephalopathy syndrome (RPLS). Her blood pressure was normal, and no other contributing factors for RPLS were found. It is likely that the initiator was the large volume of transfused blood, which disrupted cerebral autoregulation and damaged the vasculoendothelial system. Similar cases of RPLS following transfusion have been reported, and all reports involved middle-aged females with chronic severe anemia who received large volumes of transfused blood within a short period of time. Although blood transfusion is a common procedure with rare neurological complications, great caution should be taken with chronic severely anemic patients because a rapid elevation in hemoglobin may precipitate RPLS. |
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