頁籤選單縮合
題 名 | Sensitive Determination of Nanogram Levels of Diacerein in a Pharmaceutical Formulation by Flow Injection Chemiluminescence Analysis |
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作 者 | 姚寒春; 楊小峰; 李華; | 書刊名 | Journal of the Chinese Chemical Society |
卷 期 | 54:4 2007.08[民96.08] |
頁 次 | 頁949-956 |
分類號 | 341 |
關鍵詞 | Flow injection; Chemiluminescence; Diacerein; Pharmaceutical formulation; |
語 文 | 英文(English) |
英文摘要 | A simple, sensitive and inexpensive flow injection chemiluminescence (FI-CL) method for the deter-mination of diacerein was proposed. It was based on the greatly enhancive effect of diacerein on the CL reaction between luminal and hydrogen peroxide in alkaline medium. The enhanced CL intensity was linear with the concentration of diacerein over the range 1.0-500 ng/mL with a dectection limit (3σ) of 0.2 ng/mL. the relative standard deviation was 1.1% (n=8, 20ng/mL diacerein) and the sample through put was about 120 samples h-1. This simple method has been successfully applied for the determination of diacerein in a pharmaceutical formulation without interference from its potential impurities. The degradation of diacerein was also investigated briefly. |
本系統中英文摘要資訊取自各篇刊載內容。