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- Assessment with Magnetic Resonance Imaging and Spectroscopy in Lhermitte-Duclos Disease
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題名 | Assessment with Magnetic Resonance Imaging and Spectroscopy in Lhermitte-Duclos Disease=使用磁振造影影像及磁振頻譜評估Lhermitte-Duclos病 |
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作者 | 吳振豪; 蔡志文; 李貞慧; 陳文賢; 李覃; 陳啟昌; Wu, Chen-Hao; Chai, Jyh-Wen; Lee, Chen-Hui; Chen, Wen-Hsien; Lee, Tan; Chen, Clayton Chi-Cheng; |
期刊 | 中華醫學會雜誌 |
出版日期 | 20060700 |
卷期 | 69:7 民95.07 |
頁次 | 頁338-342+CA66 |
分類號 | 415.812 |
語文 | eng |
關鍵詞 | 擴散加權影像; Lhermitte-duclos病; 磁振造影影像; 磁振頻譜; Diffusion-weighted imaging; Lhermitte-duclos disease; Magnetic resonance imaging; Magnetic resonance spectroscopy; |
英文摘要 | Lhermitte–Duclos disease (LDD) is a rare benign lesion of uncertain pathogenesis characterized by distortion of the normal cerebellar laminar cytoarchitecture. We report a 22-year-old man admitted for injury sustained in a traffic accident with the incidental finding of a cerebellar mass. Magnetic resonance imaging (MRI) revealed a mass lesion within the right cerebellar hemisphere. The final diagnosis of LDD was made by obtaining a surgical specimen and identifying the characteristic appearance of the lesion by MRI study. The images showed the typical striated pattern of hyperintensity on T2-weighted images and corresponding hypointensity on T1-weighted images, as well as the typical absence of enhancement following gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA) administration. In addition, no disturbance of water diffusion on diffusion-weighted MRI, and associations of decreases in the N-acetylaspartate/creatine (NAA/Cr) and NAA/Choline (Cho) ratios with near normal values of Cho/Cr, as well as an obvious lactate peak gave supplemental information for diagnosis. |
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