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題名 | Diffuse Pulmonary Nodules with Bilateral Hilar Lymphadenopathy as a Clinical Presentation of Primary Amyloidosis with Pulmonary Involvement: A Case Report=以瀰漫性肺節結合併兩側肺門及縱膈腔淋巴結腫大做為臨床表現的肺部類澱粉沈積症:一病例報告 |
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作者 | 黃憲治; 劉榮森; 吳毅穎; 徐志育; Huang, Hsien-chih; Liu, Jung-sen; Wu, Yi-ying; Hsu, Chih-yu; |
期刊 | 胸腔醫學 |
出版日期 | 20081000 |
卷期 | 23:5 2008.10[民97.10] |
頁次 | 頁344-348 |
分類號 | 415.465 |
語文 | eng |
關鍵詞 | 肺部; 原發性類澱粉沈積症; Lung; Primary amyloidosis; |
中文摘要 | 類澱粉沈積症在臨床上被視為一種相對罕見的疾病,然而它對肺部的影響卻是很常見的。我們報告一位46歲的女性病患,以慢性咳嗽和輕微的氣促持續5週為其臨床表現。影像學顯示瀰漫性肺節結合併兩側肺門淋巴結腫大。血清蛋白的免疫電泳分析法 (immunoelectrophoresis) 及免疫固定電泳分析法 (immunofixation electrophoresis) 呈現特異性單源球蛋白IgG-λ,而肺部切片則顯示多處的類澱粉質沉積。此病灶證實為原發性肺部類澱粉沈積症。 |
英文摘要 | Amyloidosis is a relatively rare disease in clinical practice. However, pulmonary involvement in patients with amyloidosis is common. We report a 46-year-old female who presented chronic cough with mild dyspnea on exertion for about 5 weeks. Chest radiography showed diffuse pulmonary nodules with bilateral hilar lymphadenopathy. Serum protein electrophoresis followed by immunofixation electrophoresis revealed a monoclonal band of IgG-λ specificity, and multifocal amyloid deposits were found in the lung biopsy via video-assisted horacoscopic surgery. A diagnosis of primary amyloidosis with pulmonary involvement was confirmed. |
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