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題名 | Intrathoracic Paraspinal Malignant Peripheral Nerve Sheath Tumor=胸廓內脊柱旁惡性周邊神經鞘瘤 |
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作者 | 賴瑞生; 林秀玲; 許書雄; 吳銘庭; Lai, Ruay-sheng; Lin, Shong-ling; Hsu, Shu-shong; Wu, Min-ting; |
期刊 | 中華醫學會雜誌 |
出版日期 | 20060100 |
卷期 | 69:1 民95.01 |
頁次 | 頁37-41+CA07 |
分類號 | 416.293 |
語文 | eng |
關鍵詞 | 惡性周邊神經鞘瘤; 神經原生瘤; 後縱膈腔腫瘤; Malignant peripheral nerve sheath tumor; Neurogenic tumor; Posterior mediastinal tumor; |
英文摘要 | Schwannoma is the most common nerve sheath tumor in the posterior mediastinum, whereas intrathoracic paraspinal malignant peripheral nerve sheath tumor (MPNST) is quite rare. Both benign and malignant nerve sheath tumors may be symptomatic, rendering clinical differentiation of limited utility. On radiographic imaging, erosion of the ribs and vertebral bodies, irregularity in contour, and inhomogeneity in attenuation are not sufficiently reliable for diagnosis of MPNST. Histologically, MPNSTs reveal hypercellularity, nuclear atypia, and mitotic activity. Surgical resection is the main modality of treatment. Postoperative radiation therapy for MPNST has led to a significant reduction in local recurrence. The prognosis is unfavorable. Herein, we present an unusual case of a posterior mediastinal mass in a 50-year-old female with delayed diagnosis of 2 years. After surgical intervention, the histologic finding was MPNST. Postoperative radiation therapy was applied because of incomplete resection. The follow-up chest computed tomography 5 months later revealed a residual soft tissue mass with significant reduction in size over the parathoracic spine area. No neurologic sequelae were identified after surgery. |
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