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- Treatment for Psoriasis with Modified Goeckerman Regimen--One Year Experience in Southern Taiwan
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題名 | Treatment for Psoriasis with Modified Goeckerman Regimen--One Year Experience in Southern Taiwan=以修正型哥可曼療法治療乾癬病人--南臺灣一年之經驗 |
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作者 | 賴志昇; 黃柏翰; 何宜承; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 23:3 2005.09[民94.09] |
頁次 | 頁113-120 |
分類號 | 415.73 |
關鍵詞 | 哥可曼療法; 乾癬; Psoriasis; Goeckerman regimen; Tar; Ultraviolet; Phototherapy; |
語文 | 英文(English) |
中文摘要 | 雖然乾癬的治療在近年來多有進展,但許多中重度病人的治療仍是相當困難。1925年哥可曼所提出的哥可曼療法,仍被視為最有效且相對安全的療法之一。我們在2002年三月引進修正型哥可曼療法來治療台灣的中重度乾癬病人。自2002年三月至2003年五月間合計有89位病患接受過治療。其中我們共蒐集32位全身體表面積超過百分之五,且未於過去六個月內接受全身性治療,同時治療期間亦未接受口服乾癬用藥治療之病人,其乾癬面積及嚴重度指標在治療期間平均自19.4±12.4改善至4.4±3.6,且平均維持10.2±5.6個月未復發。雖然局部輕微晒傷及癢感還算常見,大致而言並沒有嚴重的副作用。在此我們報告本院一年間之初步資料,並與文獻上其他療法比較。 |
英文摘要 | Despite the recent advances in treatment for psoriasis, it is still challenging in treating patients with moderate to severe psoriasis. The Goeckerman regimen, which was introduced by Goeckerman in 1925, is still considered to be one of the most effective and relatively safe therapies for patients. We started the modified Goeckerman regimen for treating moderate to severe psoriatic patients in Taiwan in March, 2002.89 patients had been treated from March 2002 to May 2003. Among them thirty-two patients with more than 5% body surface area psoriatic lesions, who had neither systemic therapy in the past 6 months nor concurrent oral antipsoriatics during this treatment, were collected. The mean psoriasis area and severity index (PASI) scores declined from 19.4±12.4 to 4.4±3.6 during therapy, and the mean duration of remission was 10.2±5.6 months. There was no severe side effect though mild local burn and itching were fairly common. Herein we present the preliminary data and comparison to other therapies in the literature. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。