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相關文獻
- Cutaneous Manifestations of Human Immunodeficiency Virus Infection in Taiwan
- 臺灣制訂愛滋病防治政策的錯誤傾向與其引發的離心化困境
- Pulmonary Infection in Human Immunodeficiency Virus-Infected Patients in Taiwan
- Subtyping HIV-1 Infections in Taiwan Using Peptide-Enzyme Immunoassay, Reverse Transcription-Polymerase Chain Reaction, and Sequencing
- Frequency of the CCR5△32 Mutant Allele in HIV-1-Positive Patients, Female Sex Workers, and a Normal Population in Taiwan
- Autopsy Findings on Patients with AIDS in Taiwan
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- 臺灣地區愛滋病流行情況
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題名 | Cutaneous Manifestations of Human Immunodeficiency Virus Infection in Taiwan=臺灣人類免疫不全病毒感染患者的皮膚表徵 |
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作者 | 宗天一; 楊佳懿; 趙曉秋; 李玉雲; Tzung, Tien-yi; Yang, Chia-yi; Chao, Sheau-chiou; Lee, Yu-yun J.; |
期刊 | The Kaohsiung Journal of Medical Sciences |
出版日期 | 20040500 |
卷期 | 20:5 2004.05[民93.05] |
頁次 | 頁216-224 |
分類號 | 415.725 |
語文 | eng |
關鍵詞 | 皮膚表徵; CD4數值; 愛滋病; 人類免疫不全病毒感染; 臺灣; Skin manifestation; CD4 cell count; AIDS; HIV infection; Taiwan; |
中文摘要 | 人類免疫不全病毒感染患者常有皮膚症狀,且常是最先表現的症狀,台灣對於人類免疫不全病毒感染患者的皮膚表徵尚無較大規模的研究。我們回顧自 1990 年到 1998 年人類免疫不全病毒感染患者在本院皮膚科的診斷,歸納整理各種皮膚疾病發生的機率及與 CD4 數值間的關係。64 位人類免疫不全病毒感染患者,包括 38 位愛滋病患者(CD4 < 200 x 10(6) cells/L)及 26 位非愛滋病患者,共有 142 種皮膚症狀,分屬於 25 種不同種類的皮膚疾病,依發生率的高低,包括口腔的白色念珠菌感染(非愛滋病患者:15%;愛滋病患者:71%)、藥物疹、單純疹、脂漏性皮膚炎、皮癬菌感染、帶狀疹、二期梅毒、尖圭濕疣、卡波西氏肉瘤(愛滋病患者:16%)、毛狀黏膜白斑、傳染性軟疣(愛滋病患者:13%);並針對較特殊的病例做一介紹,如疣狀的單純疹病毒感染、臨床表現像尖圭濕疣的傳染性軟疣感染及與愛滋病相關的色素性紅皮症。在本篇報告中,70% 的人類免疫不全病毒感染患者有皮膚的症狀,平均每位病患合併有 2.2 種皮膚疾病(愛滋病患者:3.2 種;非愛滋病患者:0.7 種,有統計學上的差異;p < 0.001)。在此一研究中,人類免疫不全病毒感染的患者有相當多樣性的皮膚疾病,在愛滋病患有 92% 罹患與人類免疫不全病毒相關的皮膚疾病,而在非愛滋病患只有 39%,且愛滋病患皮膚病變有 78% 是在其 CD4 數值低於100 x 10(6) cells/L 以下時發生。 |
英文摘要 | Cutaneous manifestations are common and often the presenting feature of human immunodeficiency virus (HIV) infection, but a comprehensive study of HIV-associated skin lesions is not available in Taiwan. We reviewed all skin lesions in all HIV patients diagnosed in our department between 1990 and 1998 to document the spectrum of skin manifestations, the frequency of each disorder, and their relationship with CD4 counts. A total of 64 HIV patients were studied, including 38 with acquired immunodeficiency syndrome (AIDS) (CD4 < 200 x 10(6) cells/L) and 26 who had not developed AIDS (non-AIDS). There were 142 episodes of skin conditions representing 25 different skin diseases, including oral candidiasis (15% in non-AIDS vs 71% in AIDS patients), drug eruptions, herpes simplex, seborrheic dermatitis, dermatophytosis, herpes zoster, secondary syphilis, condyloma acuminatum, Kaposi’s sarcoma (16% among AIDS patients), hairy leukoplakia, and molluscum contagiosum (13% among AIDS patients), in decreasing order. Several unusual cases are briefly described, including verrucous herpes infection, condyloma-like molluscum contagiosum, and AIDS-associated pigmented erythroderma. In our study, 70% of all HIV patients had skin diseases, with an average of 2.2 conditions per patient (3.2 in AIDS patients vs 0.7 in non-AIDS patients; p < 0.001). A broad spectrum of HIV-associated skin diseases was observed in our series. The frequency of HIV-associated skin disease was 92% in AIDS patients and 39% in non-AIDS patients; 78% of skin lesions in AIDS patients were diagnosed when CD4 counts were below 100 x 10(6) cells/L. |
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