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頁籤選單縮合
題名 | Enhanced Sentinel Lymphoscintigraphic Mapping in Breast Tumor Using the Graded Shield Technique=層次遮蔽技術應用於乳房腫瘤前哨淋巴偵測造影改進 |
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作者 | 陳毓雯; 賴永昌; 徐健欽; 侯明鋒; | 書刊名 | The Kaohsiung Journal of Medical Sciences |
卷期 | 19:7 2003.07[民92.07] |
頁次 | 頁339-344 |
分類號 | 416.226 |
關鍵詞 | 層次遮蔽技術; 乳癌; 前哨淋巴結; Sentinel lymph node; Breast cancer; Graded shield; |
語文 | 英文(English) |
中文摘要 | 由於層次遮蔽技術可改善造影對比,增進淋巴結與背景活性對比,因而提高淋巴結的偵測。本研究對象為過去 6 個月期間,50 位臨床懷疑或診斷為初期乳癌女性患者(T1 及 T2),平均年齡為 47.2 ± 10.3 歲。分別以 3、5、7 公分直徑三層鉛膠片,同圓心排列,以膠水固定,為層次遮蔽器材,並以可移動式滑帶及摩術氈,正確固定及定位鉛膠片於注射點上。經由我們已發展的皮下或腫瘤邊注射技術,進行核醫藥物注射,並採同時間90 度垂直角雙頭伽瑪攝影機進行造影。比較前後使用及未使用層次遮蔽技術,於前哨淋巴偵測造影定位上,使檢測率由 74%(37/50 患者)提高至 96%(48/50 患者),具有顯著差異(p < 0.05)。本技術不單可以提高檢測率,並且提高淋巴結偵測數及容易觀察到週邊淋巴引流。由於增進偵測淋巴結與背景活性的對比,我們證明了層次遮蔽技術是有助於前哨淋巴造影偵測的一種有效方法。 |
英文摘要 | The graded shield technique was developed to increase the sentinel node detection rate by improving lymphoscintigraphic image contrast. In a 6-month period, 50 women with clinical suspicion of early stage breast cancer (T1 and T2 tumors) were enrolled in this study. The patients had a mean age of 47.2 ± 10.3 years. A composite graded shield was constructed using three concentric layers of leaded plastic measuring 3 cm, 5 cm, and 7 cm each in diameter. The graded shield was designed with a movable Velcro backing for accurate positioning over the injection site. Images were acquired with a vertical angle dual-head gamma camera using an established injection procedure developed at our institution. The rate of detection of sentinel lymph nodes using lymphoscintigraphic mapping improved from 74% (37/50 patients) to 96% (48/50) using the graded shield (p < 0.05). In addition to the increased detection rate, our technique also increased the number of nodes detected and improved visualization of the adjacent lymphatic basin. By enhancing nodal contrast, we have demonstrated that the graded shield technique is an effective method for improving the rate of sentinel node detection. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。