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題名 | Corneal Melting Associated with the Use of Topical Ketorolac: Successful Treatment with Tissue Adhesive=使用非類固醇抗炎藥物造成角膜潰瘍之成功治療病例報告 |
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作 者 | 戴明正; 張如輝; 張正忠; | 書刊名 | Journal of Medical Sciences |
卷期 | 23:4 2003.08[民92.08] |
頁次 | 頁227-229 |
分類號 | 416.711 |
關鍵詞 | 非類固醇抗炎藥物; 角膜潰瘍; Corneal melt; Kerarolac tromethamine; Nonsteroid anti-inflammatory drugs; |
語文 | 英文(English) |
英文摘要 | We report a case of corneal melting associated with the use of topical nonsteroid anti-inflammatory drugs (Kerarolac tromethamine, Acular®). A 78-year-old male with history of dry eye syndrome was referred for evaluation of corneal melting in his right eye. By history he had undergone uncomplicated cataract surgery of right eye 2 months previously, and had been on topical tobramycin-dexamethasone drops 4 times daily after surgery. One month later he was prescribed Acular 4 times daily for corneal edema with folding. Examination disclosed visual acuity 20/200 in the right eye. Two epithelial defects with stromal thinning were noted: One 1.0×0.8 mm defect in the area of previous temporal cataract wound with 50% tissue loss, the other 1.8×1.0mm defect inferior paracentral ulcer with 90%tissue loss. There was no anterior chamber reaction and no corneal infiltrate. He was treated with erythromycin ointment every 3 hours, ofloxcin 4 times daily and cyanoacrylate glue and bandage contract lens was placed over paracentral lesion. The 2 ulcers healed within 2 months with residual stromal thinning and scarring. The uncorrected visual acuity was 20/40 in the right eye at last follow-up. |
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