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題名 | Persistent Hyperplastic Primary Vitreous: Magnetic Resonance Imaging and Clinical Findings=持續存在之增生性初級玻璃體--核磁共振掃描影像和臨床症候之表現 |
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作者 | 孫銘輝; 高玲玉; 郭雅慧; | 書刊名 | 長庚醫學 |
卷期 | 26:4 2003.04[民92.04] |
頁次 | 頁269-276 |
分類號 | 416.74 |
關鍵詞 | 持續存在之增生性初級玻璃體; 核磁共振掃描; 惡性視網膜母細胞瘤; 柯滋式病; Persistent hyperplastic primary vitreous; PHPV; Magnetic resonance image; Retinoblastoma; Coats' disease; |
語文 | 英文(English) |
中文摘要 | 背景:本文指在提出持續存在之增生性初級玻璃體(persistent hyperplastic primary vitreous)其在眼精前房及後房的核磁共振掃描影像之表現以便利於與其他易和此病病混浠的眼內異常疾病相鑑別。 方法:蒐集17位有持續有存在之增生性初級玻璃體並且做過核磁共振掃描的病人,紀錄其核磁共振掃描像和臨床症候之表現。 結果:總共17個病人當中(6位男性,11位女性),有13位是單測發生(11個在左眼,2個在右眼)四位是雙側發生,持續存在之增生性初級玻璃體在眼精前房的檢磁共振掃描影像之表現包括有前房狹窄或塌陷、前房發育異常、及水加體後之血管膜,此種血管膜加顯影劑後呈現高度顯影。而其在眼精後房的影像表現有:一、小眼球;二、管狀影像,它代表玻璃狀體動脈;三、漏斗狀視網膜剝離,此視網膜下液體在T1及T2影像下呈現高度亮區;四、液狀介面,它在T1及T2影像對呈現暗區。它代表的是視網膜下出血;五、水晶體後腫塊;六、玻璃體出血。病人最常見的臨床表現是小眼球,前房狹窄或塌陷,以及白色瞳孔。 結論:持續存在之增生性初級玻璃體在不同階段其在眼精內的表現呈現多樣化,而它在核磁共振掃描影像上的表現配合臨床上的表徵可以利於和其他眼內疾患如惡性視網膜母細胞瘤(Retinoblastoma)、柯滋式病(Coats’s disease)等相鑑別。 |
英文摘要 | Background: This study presents magnetic resonance imaging (MRI) findings of both the anterior and posterior types of persistent hyperplastic primary vitreous (PHPV) to facilitate the differential diagnosis from other intracocular abnormalities. Methods: Seventeen patients with PHPV who were evaluated using non-contrast and contrast-enhanced T1- and T2-weighted images were retrospectively reviewed. Results: Among the 17 patients with PHPV (6 males, 11 females), 13 had unilateral PHPV (11 left eyes, 2right eyes), and 4 had bilateral PHPV. The MRI findings of the anterior type of PHPV included a shallow or collapsed anterior chamber, an anterior segment anomaly, and a retrolental vascular membrane which demonstrated hyperintensity after contrast enhancement. The MRI findings of the posterior type consisted of microphthalmos; a tubular image, representing the hyaloid vessel; a funnel-shaped retinal detachment, with the subretinal fluid hyperintense on both T1- and T2-weighted images; the fluidfluid level, which was hypintense on both T1-and T2-weighted images and probably corresponded to the presence of hemorrhage in the subretinal space; a retrolental mass; and vitreous hemorrhage. The most common clinical presentations of patients with PHPV in our study were microphthalos, a shallow or collapsed anterior chamber, and leukocoria. Conclusions: The presentation of PHPV at different stages was variable; the MRI features of PHPV along with clinical findings were able to facilitate the differential diagnosis for other intraocular abnormalities such as retinoblastoms and Coats’ disease. |
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