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題名 | Bromelain Catalyzed Synthesis of Peptides in Organic Solvent |
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作者 | 戴達夫; 傅淑玲; | 書刊名 | Journal of the Chinese Chemical Society |
卷期 | 50:1 2003.02[民92.02] |
頁次 | 頁179-183 |
分類號 | 346.01 |
關鍵詞 | Bromelain; Peptide synthesis; Aspartame; Organic solvent; |
語文 | 英文(English) |
英文摘要 | For the first time, immobilized bromelain was shown to maintain high catalytic activity in organic solvent and to form peptide bonds. It requires only 7 hours to obtain Cbz-Gly-L-Leu-OMe in 85% yield. The precursor of aspartame (Cbz-L-Asp-L-Phe-OMe) and other dipeptides were also synthesized by this method. |
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