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題名 | 基底細胞癌--臺灣南部某醫學中心109例病例分析=Basal Cell Carcinoma: The Analysis of 109 Cases in a Southern Medical Center in Taiwan |
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作者 | 朱瑞景; 劉文德; 柯中文; | 書刊名 | 臺灣家庭醫學雜誌 |
卷期 | 12:2 2002.06[民91.06] |
頁次 | 頁49-57 |
分類號 | 415.78 |
關鍵詞 | 基底細胞癌; 皮膚惡性腫瘤; Basal cell carcinoma; Skin cancer; Arsenical keratosis; Incidence; |
語文 | 中文(Chinese) |
中文摘要 | 基底細胞癌(basal cell carcinoma)在亞洲人身上並不常見,因此有關於臺灣基底細胞癌病患的臨床研究也較少,本文是收集從1994年至2001年間,在奇美醫院診斷為基底細胞癌的病患為樣本,八年來共109例。分別就性別與年齡的分佈、病患的職業、病灶的數目與部位、臨床表徵、復發與遠處轉移,以及合併砷角化症和其他癌症的比例作分析。本研究樣本數男:女比例為1.09:1,年紀最小為37歲,最大為87歲,平均年齡為66歲;病患職業主要以農漁業為主;病灶主要分佈在頭頸部佔83.5%,臨床上75%的病灶為色素性基底細胞癌,17人出現多發性病灶,這明顯比之前日、韓和歐美的報告都來的高,顯示南部民眾可能因地緣及職業易受日光曝曬過度,以及沿海水質遭砷污染的緣故而較易出現多發性的皮膚病變。接受治療並追踪至今的86人中,六人有病灶復發,但沒有人發生遠處轉移。由於南部地區的日照較為強烈,相對的皮膚癌變機率也較高。所以,一旦發現皮膚上有了不正常的色素沈積時,積極的切片檢查以及適當的病灶切除乃是最佳的治療方式。 |
英文摘要 | Basal cell carcinoma (BCC) is common in the Asian people. Thus, there is limited data describing the clinical manifestations of BCC among Taiwanese patients. A total of 109 patients with BCC between 1994 and 2001 were retrospectively examined at Chi-Mei Foundation Hospital. We analyzed the annual number of new case, sex and age distribution, patients' occupations, numbers and sites of the lesions, clinical appearances, recurrence, metastasis of tumors, and accompanied by arsenical keratosis or other cancer. The male-to-female ratio was 1.09, and their ages ranged from 37 to 87, with an average age of 66. The main occupations of our patients were farmers and fishers. The head and face were two main sites involved. Clinically, 75% of the tumors were pigmented. Multiple lesions occurred in 17 patients, which is much higher than those reports in Japan, Korea, America and Europe. The result suggests that the people who reside in southern Taiwan tend to have multiple skin lesions due to excessive sun-exposure and water pollution. There were 86 patients who have received treatment and follow-up so far. Six tumors recurred and none of them was metastasized. Because of heavy sun-exposure in southern Taiwan, leading to the higher risk of skin cancer development, aggressive skin biopsy and excision are suggested if the skin lesion appears abnormally pigmented. |
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