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| 題 名 | Systematical Synthesis of Distamycin Analogues and their Interaction with Herring Sperm DNA |
|---|---|
| 作 者 | 湯菲力; 王津; 劉丹; 李經建; 袁谷; | 書刊名 | Journal of the Chinese Chemical Society |
| 卷 期 | 49:6 2002.12[民91.12] |
| 頁 次 | 頁1073-1077 |
| 分類號 | 361.4 |
| 關鍵詞 | Distamycin; Synthesis; Chloroform reaction; Fluorescence; DNA; |
| 語 文 | 英文(English) |
| 英文摘要 | A simple procedure for the systematical synthesis of eight distamycin analogues containing N-methyl- pyrrole (Py) and N-methylimidazole (1m) has been developed by a chloroform reaction and DCC coupling reaction without amino protection and deprotection, and the interaction of the analogues with Herring Sperm DNA was investigated by fluorescence spectroscopy. |
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