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題名 | Isolated Sphenoid Sinus Aspergillosis: Report of Two Cases=單獨性蝶竇麴菌症--二例報告 |
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作者 | 李達人; 黃祥富; 黃啟哲; 陳盈霖; | 書刊名 | 長庚醫學 |
卷期 | 25:7 2002.07[民91.07] |
頁次 | 頁464-468 |
分類號 | 416.853 |
關鍵詞 | 蝶竇; 麴菌症; Sphenoid sinus; Aspergillosis; |
語文 | 英文(English) |
中文摘要 | 麴菌廣佈於環境中,且是副鼻竇黴菌感染中最常見之致病原。雖然如此,單獨性蝶竇麴菌瘧於健康人身上發生的機會相當罕見。本文提出兩病患:一為53歲女性病患,因鼻涕倒流中帶血2週至門診求診;另一為61歲女性病患因左側臉腫有2個月至門診求診。於電腦斷層攝影上,可見中央高密度區,此被視為副鼻竇麴菌症感染的特徵。本文中兩例皆以鼻竇功能內視鏡手術處理,追蹤6個月皆無復發。回顧文獻,單獨性蝶竇麴菌症有好發於中老年女性病患之傾向,對此,吾人認為中老年齡婦女體內的荷爾蒙改變與此應有相關。於非侵犯型麴菌病中,抗黴菌藥物並不建議常規使用,手術治療扮演較重要之角色。 |
英文摘要 | Aspergillus fungus can be found worldwide and is the most common fungal infection of the paranasal sinuses. Despite this ubiquity, aspergillosis of the sphenoid sinus as an isolated disease in an otherwise healthy person is quite rare. We report two cases in this article: one was a 53-year-old woman who suffered from bloody postnasal drip for 2 weeks and the other a 61-year-old woman suffered from facial swelling for 2 months. Central dense areas, which are characteristic for Aspergillus sinus infection, were found on their computer to mographs. Both patients were managed by functional endoscopic sinus surgery without recurrence within the 6-month follow-up period. A survey of the reports in the literature indicated that the occurrence of isolated sphenoid sinus aspergillosis was predominantly in elderly females. Hormone changes which occur during this age might play a role in the pathogenesis of fungal infection. Treatment with an anti-fungal agent was not suggested for non-invasive aspergillosis. Instead, surgery played a major role in the treatment. |
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