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| 題 名 | Syntheses of 5-(3-Arylsydnon-4-yl)tetrazole Derivatives |
|---|---|
| 作 者 | 施美秀; 李美津; 葉茂榮; | 書刊名 | Journal of the Chinese Chemical Society |
| 卷 期 | 49:3 2002.06[民91.06] |
| 頁 次 | 頁361-368 |
| 分類號 | 346.01 |
| 關鍵詞 | Sydnones; Nitrile oxides; Carbohydroximic acid; Chlorides; Azidoximes; Tetrazoles; 3-Arylsydnone-4-carbazidoximies; 1-Acyloxy-5-(3-arylsydnon-4-yl)trazoles; 1-Hydroxy-5-(3-arylsydnon-4-yl)tetrazoles; |
| 語 文 | 英文(English) |
| 英文摘要 | 3-Arylsydnone-4-carbohydroximic acid chlorides (1) could react with sodium azide to produce the corresponding 3-arylsydnone-4-carbazidoximes (2), but not 1-hydroxytetrazoles 3. Treatment of 3-arylsydnone-4-carbazidoximes (2) with acid chlorides such as acetyl chloride (4a), propionyl chloride (4b) and benzoyl chloride (4c) in the presence of excess triethylamine generated the derivatives of the azidoximes 5. To obtain the desired tetrazoles, the azidoximes 2 should first cyclize directly with acetyl chloride (4a) or propionyl chloride (4b) to afford the acetyl or propionyl derivatives 6. The cyclized tetrazole derivatives 6 underwent deacylation upon heating in ethanol to give 1-hydroxy-5-(3-arylsydnon-4-yl)tetrazoles (3). |
本系統中英文摘要資訊取自各篇刊載內容。