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頁籤選單縮合
題名 | Extreme Insulin Resistance Syndrome=極度胰島素抗性症候群 |
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作者 | 陳光文; 莊峻鍠; 林仁德; | 書刊名 | 長庚醫學 |
卷期 | 24:10 2001.10[民90.10] |
頁次 | 頁640-645 |
分類號 | 415.66 |
關鍵詞 | 胰島素抗性; 糖尿病; Rabson-mendenhall 症候群; Insulin resistance; Diabetes mellitus; Rabson-mendenhall syndrome; |
語文 | 英文(English) |
英文摘要 | Congenital extreme insulin resistance syndrome has rarely been reported in Taiwan. In 1982, a girl of a consanguineous marriage was noted to have increased body hair, an enlarged clitoris, and acanthosis nigricans at birth. Two months later, she received an operation for bilateral polycystic ovaries. She was found to have diabetes at 8 years old and was treated with insulin. In March 1999, she was referred to our clinic with growth retardation and poor glycemic control. She had a characteristic face with a saddle nose, broad mouth, large low-set ears, absence of subcutaneous fat, and deformed nails. Although a very high dose of insulin (> 10 IU/kg/day) was used, her glycemic control was very poor (HbA1c 13.8%). Pediatricians should remain alert for the manifestations of extreme insulin resistance. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。