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題名 | Infantile Hemangioendothelioma with a Highly Elevated Serum Alpha-fetoprotein Level: Report of a Case=伴隨α胎兒蛋白血漿值昇高的嬰幼兒血管內皮瘤:一病例報告 |
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作者姓名(中文) | 簡紹南; 王萬龍; 廖承藝; 羅道琦; | 書刊名 | 中臺灣醫學科學雜誌 |
卷期 | 5:1 2000.03[民89.03] |
頁次 | 頁59-63 |
分類號 | 417.526 |
關鍵詞 | α胎蛋白; 血管內皮瘤; 肝母細胞瘤; Alpha-fetoprotein; Hemangioendothelioma; Hepatoblastoma; |
語文 | 英文(English) |
中文摘要 | 嬰幼兒肝臟的血管內皮瘤是在出生後第一年內小兒間質的腫瘤中最常見及主要的一種,約80-90%的腫瘤是發生在前6個月。一個足月的新生女嬰在出生後腹部發現腫塊,腹部超音波及電腦斷層掃描顯示瀰散的左肝結節伴隨細緻的彎曲線型鈣化。昇高的α胎兒蛋白血漿值誤導我們有肝母細胞瘤(hepatoblastoma)的初步印象。然而,外科手術摘除後的病理報告發現是肝臟血管內皮瘤(hemangioendothelioma)。這個病例顯示一些新生兒的α胎兒蛋白血漿值在出生後前2個月常有昇高到400 ng╱ml 的情形。我們必需要謹慎評估這種數值,尤其是當其伴隨有肝腫瘤的時候更是如此。 |
英文摘要 | Infantile hemangioendothelioma of the liver is the most common primary pediatric mesenchymal tumor during the first year of life, with 80%-90% of tumors occurring during the first 6 months of life. A full-term, newborn girl was found to have an abdominal mass after delivery. Abdominal ultrasonography and computed tomography (CT) demonstrated diffuse left hepatic nodules with fine curvilinear calcification. A highly elevated alpha-fetoprotein (AFP) level misled us to the impression of hepatoblastoma; however, the pathologic reports through a surgical resection disclosed liver hemangioendothelioma. The patient did well 3 weeks after surgery. This case emphasizes that an elevated AFP level of up to 400 ng/ml is normally found in some neonates until two months of age. Careful interpretation of this value is very important, especially when it is associated with a hepatic tumor. |
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