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題名 | Extraskeletal Intracranial Mesenchymal Chondrosarcoma: Case Report and Literature Review=骨骼系統之外的顱內間質軟骨肉瘤:病例報告及文獻回顧 |
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作者 | 陳俊逸; 許書雄; 何治軍; Chen, Jun-yih; Hsu, Shu-shong; Ho, Jih-tsun; |
期刊 | The Kaohsiung Journal of Medical Sciences |
出版日期 | 20040500 |
卷期 | 20:5 2004.05[民93.05] |
頁次 | 頁240-246 |
分類號 | 416.66 |
語文 | eng |
關鍵詞 | 腦部腫瘤; 顱內腫瘤; 間質軟骨肉瘤; Brain neoplasm; Intracranial tumor; Mesenchymal chondrosarcoma; |
中文摘要 | 骨骼系統之外的顱內間質軟骨肉瘤非常罕見,自從 1962 年首次報告以來,總共只有 36 例而已。本文描述一位 13 歲的女性,主訴持續一個月的頭痛、複視、噁心、嘔吐,伴隨雙側視乳頭水腫、外旋神經麻痺及右側肢體無力。腦部影像學檢查顯示兩側額葉及左側頂葉之巨大腫瘤,患者並無其他顱外異常病灶,術前診斷為惡性腦膜瘤。病患接受顯微開顱術將腫瘤完全切除。術後之病理報告為間質軟骨肉瘤。患者術後並未接受放射或化學治療,於門診追蹤 30 個月後之腦部磁振造影檢查亦無發現腫瘤復發跡象。文獻回顧顯示此惡性腫瘤容易局部復發與遠處轉移,大部分案例建議儘可能手術根除以及術後密切追蹤,可以獲得較長期的存活。而放射治療與化學治療的效果仍未有定論,僅建議用於手術無法完全切除腫瘤的病患作為輔助療法。 |
英文摘要 | We present the case of a 13-year-old girl with a huge intracranial mesenchymal chondrosarcoma. She had suffered from severe headache, diplopia, intermittent nausea and vomiting for 1 month. Neurologic examination revealed bilateral blurred optic disc margins and abducens paresis. Magnetic resonance imaging demonstrated a giant, heterogeneous, intensely enhancing mass of 7 x 8 x 6 cm, occupying the bilateral frontal and left high parietal regions and based on the anterior cerebral falx. A presumptive diagnosis of aggressive meningioma was made. The patient underwent bicoronal craniotomy and gross total resection of the tumor. Pathologic examination revealed an extraskeletal mesenchymal chondrosarcoma. She was under regular follow-up and remained free of recurrence after surgery. In addition to the current case, we review previously reported cases of extraskeletal intracranial mesenchymal chondrosarcoma and discuss treatment strategies and outcomes. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。