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頁籤選單縮合
題名 | Effects of Norepinephrine on Isolated Rabbit Aorta at Different Temperatures=不同溫度下Norepinephrine對於家兔主動脈血管收縮之影響 |
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作者 | 蔡輝彥; 朱秋玲; 謝文聰; 陳玉芳; 李正淳; Tsai, Huei-yann; Chu, Chiou-ling; Hsieh, Wen-tsong; Chen, Yuh-fung; Lee, Cheng-chun; |
期刊 | 中臺灣醫學科學雜誌 |
出版日期 | 19990300 |
卷期 | 4:1 1999.03[民88.03] |
頁次 | 頁57-61 |
分類號 | 381.18 |
語文 | eng |
關鍵詞 | 不同溫度; 血管平滑肌; Different temperatures; Norepinephrine; Vascular smooth muscle; |
中文摘要 | 體溫的變化是影響生物體生理功能的因素之一,早期有學者提出溫度對於兔子體表動脈血管(cutaneous arteries)具影響,並發現低溫會引起內皮(endothelium)產生一氧氮(nitric oxide, NO)舒張血管,以防止血管因低溫過度攣縮(cold-induced cutaneous vasospasm),對於深層血管(deep vessels)例如主動脈血管(aorta)的溫度連續變化的影響研究報告尚少。本實驗結果顯現,當存在血管的溫度低於37℃時,其收縮力較弱;隨著溫度增加,收縮力增加;反之,隨溫度降低,血管收縮力亦降低,呈現溫度依存性(temperature-dependence)。並且觀察到norepinephrine在不同溫度時收縮力亦不同,37℃時血管收縮力最大,而20℃時收縮力最小。由以上實驗顯示,在家兔的離體主動脈血管實驗中,器官槽中的溫度選擇以35℃至37℃反應能力最佳。 |
英文摘要 | The charge in body temperature is one of the most important factors in physiological functions. Early studies have suggested that the cutaneous arteries of the rabbit are influenced by temperature changes. Low temperature stimulates the release of nitric oxide from the endothelium and prevents cold-induced casospasm by relaxation of the vessels. However, the influence of temperature changes on deep vessels I sot clear. The preparation of isolated rat aortic strips was used in this study. The temperatures in the organ bath were changed, using a thermometer as a guide. Form our results, the isolated rabbit aorta relaxed when the organ bath temperature was lowered from 37℃ to 20℃. The tension of the vascular smooth muscle increased when the temperature was increased from 20℃ to 37℃. Norepinephrine-induced contraction in the isolated rabbit aorta was influenced by different temperatures. The optimal temperature for the isolated rabbit aorta was 35℃ to 37℃in the in vitro experiment. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。