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頁籤選單縮合
題名 | 某醫學中心新生兒加護病房的院內感染--分析十年的研究報告=Nosocomial Infection in a Neonatal Intensive Care Unit: A Ten-Year Analysis in a Medical Center |
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作者 | 林英智; 陳伯彥; 陳昭惠; 王德明; 遲景上; 劉有增; Lin, Ing-jing; Chen, Po-yen; Chen, Chao-huei; Wang, Teh-ming; Chi, Ching-shiang; Lau, Yeu-jun; |
期刊 | 院內感染控制雜誌 |
出版日期 | 19990400 |
卷期 | 9:2 1999.04[民88.04] |
頁次 | 頁65-74 |
分類號 | 419.38 |
語文 | chi |
關鍵詞 | 新生兒; 院內感染; 新生兒加護病房; Neonates; Nosocomial infection; Neonatal intensive care unit; |
中文摘要 | 研究分析近十年來本院新生兒加護病房內的院內感染率,感染菌種,抗藥性的變遷,以及對病人預後的影響。回溯分析從1988年1月到1997年12月住進本院新生兒加護病房的病人,符合院內感染標準定義的個案,詳細的研究其病歷、分析基本資料、感染部位、病原菌、抗生素的敏感性試驗結果、臨床表徵、可能危險因素、治療過程、預後及併發症。然後比較在不同出生體重病人發生率和造成預後的影響及差別。結果發現本院新生兒加護病房的院內感染率從1988年的2.1%增加到1997年18.6%。最常發生的部位是血流感染(59.9%),其次為肺炎(23.8%)。造成血流感染的最主要菌種為Coagulase-negative staphylococci, CNS(28.4%)及黴菌(26.7%)。出生體重小於1,500公克的早產兒其院內感染率為33.6%,大於1,500公克的早產兒其院內感染率為4.7%。不論何種出生體重組別,有發生院內感染者,其住院天數都較長(p<0.05)。近年來本院新生兒加護病房內的院內感染率有增加的趨勢,院內感染會延長病人的住院天數,且極低體重的早產兒有相當高的院內感染率。進一步分析造成高院內感染率的因素及減少院內感染是目前最迫切的課題。 |
英文摘要 | To investigate the epidemiology of nosocomial infection in our neonatal intensive care unit (NICU) and the influence of nosocomial infection in different birth weight patients, we retrospectively reviewed the patients admitted to our NICU from Jan. 1988 to Dec. 1997. Newborn infants aged younger than one month and admitted to our NICU longer than 48 hours were included. The charts of patients with nosocomial infection were reviewed in detail. The nosocomial infection rate increased from 2.1% in 1988 to 18.5% in 1997. The most common type of nosocomial infection is blood stream nfection (59.9%). Coagulase-negative staphylococci (28.4%) and fungi (26.7%) are the first two most common pathogens of nosocomial blood stream infection. The nosocomial infection rate was 33.6% for infants of birth weight less than 1,500 g and was 4.7% for those more than 1,500g. The total hospitalization days for patients with nosocomial infection all were longer than those without nosocomial infection (p<0.05). We conclude that the nosocomial infection rate has significantly increased in recent years, the patients with lower birth weight had the higher nosocomial infection rate and the nosocomial infection would prolong the hospitalization days. Further investigations to develop the strategy for preventing nosocomial infection in our NICU, especially in very low birth weight babies, are warranted. |
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