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題名 | Disseminated Cytomegalovirus Disease in a Patient with Systemic Lupus Erythematosus not Undergoing Immunosuppressive Therapy=未經免疫抑制劑治療之紅斑性狼瘡病人罹患瀰漫性巨細胞病毒感染 |
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作者 | 古世基; 余忠仁; 張逸良; 楊泮池; | 書刊名 | 臺灣醫學會雜誌 |
卷期 | 98:12 1999.12[民88.12] |
頁次 | 頁855-858 |
分類號 | 415.761 |
關鍵詞 | 免疫抑制劑; 紅斑性狼瘡; 瀰漫性巨細胞病毒感染; Systemic lupus erythematosus; Cytomegalovirus disease; Immunosuppressive therapy; |
語文 | 英文(English) |
英文摘要 | We describe a case of cytomegalovirus (CMV) infection in a 25-year-old woman with a 3-year history of systemic lupus erythematosus (SLE) with persistently high disease activity, who had not received immunosuppressive therapy. Disseminated CMV infection presented with upper gastrointestinal bleeding, high fever, respiratory distress, leukopenia, and thrombocytopenia. The CMV infection was successfully treated with combined antiviral and immunoglobulin therapy, and the SLE activity decreased concomitantly. CMV disease is closely related to host immunosuppression, primarily T-lymphocyte dysfunction. This case should highlight the relationship between clinically significant CMV disease and compromised immunity in patients with active SLE who are not receiving immunosuppressive therapy. |
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