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題 名 | Cardiovascular Function in Young Patients with Type 1 Diabetes Mellitus=第一型糖尿病青少年的心臟功能 |
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作 者 | 陳銘仁; 李燕晉; 許瓊心; 高信安; 黃富源; | 書刊名 | 臺灣兒科醫學會雜誌 |
卷 期 | 40:4 民88.07-08 |
頁 次 | 頁250-254+290 |
分類號 | 415.6682 |
關鍵詞 | 第一型糖尿病; 左心室功能; 腎功能; Type 1 diabetes; Left ventricular function; |
語 文 | 英文(English) |
中文摘要 | 我們利用心臟超音波檢查研究47位第一型糖尿病人的左心室功能,包括左心室 肌質塊、心輸出量、收縮指數以及左心室舒張期容積等,對照這47位病人及30位年齡、身 高及體重相仿的健康對照組青少年的結果發現,第一型糖尿病人其左心室功能較對照組稍 高,但其中只有心輸出量一項具有統計學上之意義(p=0.06)。可能的原因是我們第一型糖尿 病人的患病期間較短所致(平均4.02±4.07年)此外,以單一因素來比較,第一型糖尿病人 的左心室肌質塊與其心輸出量、血壓及左心室心收縮力分別具有正相關性,同時左心室收縮 力與收縮及舒張壓亦具有正相關性。至於腎功能方面如尿中白蛋白排出量,糖尿病人患病期 間、糖化血紅素、血清肌酸酐等與左心室收縮力並無統計學上之相關性。 |
英文摘要 | Echocardio graphic assessment of cardiovascular function was performed in 47 type 1 diabetic patients and 30 healthy control subjects of comparable age, height, weight, and heart rate. Indexed left ventricular mass, stroke volume, cardiac output, cardiac index, shortening fraction, indexed diastolic dimension, and indexed diastolic volume were calculated and compared between patient and control groups. Left ventricular mass and performance were slightly elevated in type 1 diabetic patients compared with 30 healthy control individuals. However, only cardiac output had borderline statistical significance (p= 0.06). The reason might be short duration (mean, 4.02±4.07 years) of diabetes in our patients group. In 18 of 47 patients the duration of type 1 diabetes was even less than two years. Relation of left ventricular mass to independent variables showed that, left ventricular mass was significantly correlated with stroke volume (p=0.008), cardiac index (p=0.0005), indexed systolic blood pressure (p=0.0000199), indexed diastolic blood pressure (p=0.0000172) and left ventricular contractility (p=0.000273) in diabetic patients. Left ventricular contractility was also independently associated in diabetic patients with the indexed systolic and diastolic blood pressure (p=0.0000755 and 0.000678 respectively). Albumin excretion, duration of diabetes, glycosylated hemoglobin (HbAlc), serum creatinine, and left ventricular pre load did not have significant univariate correlation with left ventricular contractility. |
本系統中英文摘要資訊取自各篇刊載內容。