頁籤選單縮合
題名 | Alcalase-catalyzed Synthesis of Novel 2,6-Dimethoxyhydroquinone-3-mercaptoacetyl-peptide Conjugates= |
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作者 | 陳文復; 莊明珠; 陳水田; 佘亮; Chen, Wen-fu; Jong, Ming-chu; Chen, Shui-tein; Sheh, Leung; |
期刊 | Journal of the Chinese Chemical Society |
出版日期 | 19990200 |
卷期 | 46:1 1999.02[民88.02] |
頁次 | 頁127-129 |
分類號 | 340 |
語文 | eng |
關鍵詞 | Alcalase-catalyzed syntheses; Peptide conjugates; |
英文摘要 | Seven dipeptide and one tripeptide conjugates of the cytotoxic drug 2,6-dimethoxyhydroquinone-3-mercaptoacetic acid (DMQ-MA) conjugates were prepared successfully by an alcalase-catalyzed reaction in alcohols, using DMQ-MA-X-OMe as the acyl donor and H□N-Y-CONH□ as the nucleophile (where X and Y are ammo acids, and amino acid/dipeptides, respectively). |
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