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題名 | Malacoplakia in a Colonic Adenoma: Case Report=大腸軟化斑併有管狀腺瘤:病例報告 |
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作者 | 張菡; 郭健龍; Chang, Han; Kwok, Chien-long; |
期刊 | 長庚醫學 |
出版日期 | 19980900 |
卷期 | 21:3 1998.09[民87.09] |
頁次 | 頁318-322 |
分類號 | 415.569 |
語文 | eng |
關鍵詞 | 腺瘤; 大腸; 軟化斑; Adenoma; Colon; Malacoplakia; |
中文摘要 | 本文報告一個大腸軟化斑(malacoplakia)併有管狀腺瘤(tubular adenoma)的案例 。這是一位67歲男性病人患有精神官能症達10年之久,並且有接受藥物控制中。於1997年 1月間,病人做一次健康檢查,檢查情況大致良好;僅在常規大腸鏡檢查中,發現在降結腸 處有一個息肉,立即做息肉切除(polypectomy)並送病理檢查,病理切片檢查為大腸軟化斑 併有管狀腺瘤。回顧文獻中發現大腸軟化斑常合併有其他疾病,其中又以惡性腫瘤最常見; 至於合併管狀腺瘤者相當少見,包括本文此例,共僅有 3例報告。我們整理文獻中有關大腸 軟化斑的臨床表現,治療方法及其預後等均詳列於內文中並加以討論。我們認為大腸軟化斑 的發生率要比報告病例來得多。仔細的病理組織學檢查是需要強調的。 |
英文摘要 | We Report a case of Colonic malacoplakia in a tubular adenoma. A 67-year-old neurotic man had been treated with minor tranquilizers for 10 years. In January 1997, he underwent a health examination. Most of the tests performed were within normal limits, except the colonoscopy, which revealed a polypoid lesion in the left colon. A polypectomy was performaed at that time. The histopathological study of the polyp showed a tubular adenoma with malacoplakia, characterized by an aggregate of numerous histiocytes containing michaelis- Gutmann bodies in the lamina propria. A review of the English literature indicated that 35 cases of colonic malacoplakia have been documented. Colonic malacoplakia can occur in isolation or with diffuse or multiple involvement of the adjacent and unrelated diseased sites. The majority of cases are associated with other diseases, the most common being carcinoma of the colorectum. The association of colonic malacoplakia with adenoma is extremely rare and only 3 cases including our present case have been reported. We suggest that colonic malacoplakia is more common than usually suspected. A careful histologic examination is necessary. |
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