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題名 | 第一期低惡性卵巢黏液囊狀瘤的保守治療=Conservative Management for Stage I Mucinous Cystadenoma of Low Malignant Potential of the Ovary: a Study of 30 Case and Literature Review |
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作者 | 屠乃方; 陳信義; Twu, Nae-fang; Chen, Sidney S.; |
期刊 | 中華民國婦癌醫學雜誌 |
出版日期 | 19980400 |
卷期 | 1998:1 1998.04[民87.04] |
頁次 | 頁1-7 |
分類號 | 417.25 |
語文 | chi |
關鍵詞 | 卵巢黏液囊狀瘤; 低惡性; 保守性治療; |
中文摘要 | 低惡性卵巢黏液囊狀瘤(mucinous cystadenoma of low malignant potential of th ovary)病人有很好的預後,但在治療上其手術的範圍有很大的差異性。我們統計分析長島猶太醫學中心(Long Island Jewish Medical Center)這類的病人,希望了解保守性手術(conservative surgery)用於第一期疾病治療的可能性。我們收集了長島猶太醫學中心婦產部自1975年至1996年間所有的卵巢腫瘤病例,發現共有78例低惡性卵巢瘤,其中30例為低惡性卵巢黏液囊狀瘤。此30例病人的平均年齡為51歲(22-76),平均追蹤時間為7.9 年(1月-21.8年)。30人中有28人為第一期疾病(90.3%),其中10人(35.7%)是接受保守性手術而且復發率只有10%。疾病不分期整體的5年及10年存活率分別是97.7% 和3.3%,而第一期存活率更高達100%。我們合併統計其他作者已發表的10篇文章301位病人,在加起來全部共331位低惡性卵巢黏液囊狀瘤病人中,有304位是第一期疾病。其中139人(45.7%)接受保守性手術,只有6人復發(4.3%)。手術後懷孕率為14.3%(6/42)。此研結果告訴我們,對於第一期低惡性卵巢黏液囊狀瘤病人,採取保守性手術以保留生育能力是可行的治療模式。 |
英文摘要 | Unlike invasive carcinoma, patients with mucinous cystadenoma of low malignant potential (LMP) of the ovary have good prognosis. Treatments of mucinous tumors of LMP of the ovary are diverse ranging from simple cystectomy to maximal surgery. This study of 30 cases with literature review if undertaken to assess the potential of conservative surgery for mucinus tumors of LMP in stage Ⅰ disease. Seventy-eight cases of ovarian tumor of LMP were collected from 1975 to 1996 at Long Island Jewish Medical Center. Thirty cases of mucinous tumor of LMP entered this study. The mean age of patients was 51 (22-76), the mean of follow-up was 7.9 years (1 month-21.8 years). Twenty-eight patients (90.3%) were stage Ⅰ disease, 10 (35.7%) of them underwent conservative surgery with 1 (10%) recurence. The 5-year and 10-year survival rate in all stage was 96.7% and 93.3%, respectively. The survival rate in stage Ⅰ disease was 100%. Combined with 301 cases of mucinous tumor of LMP in 10 reviewed series and the present study, 331 cases of mucinous tumor of LMP were studied. Of 331 casease, 304 cases (91.8%) were stage Ⅰ disease. Among these cases in stage Ⅰ disease, 139 patients (45.7%) underwent conservative surgery with only 6 (4.3%) recurrences developed. Six (14.3%) of 42 patients reported by five series of investigators had subsequent pregnancies following the surgery. Based on our study, conservative surgery for stage Ⅰ mucinous tumors of LMP might be considered for women for reproductive age, except for patients with a strong family history of ovarian cancer, breast cancer. Completer surgery might be considered for postmenopausal women, patients with advanced stage, or who had completion of their family after conservative surgery. Those have been treated conservatively, longer follow-up surveillance is desirable. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。