查詢結果分析
相關文獻
- 利用相間轉移觸媒合成對-羥基苯甲酸丁酯之研究
- 相間轉移催化合成醋酸苯甲酯之研究
- A Theoretical Model for Phase Transfer Catalyzed Reaction with the Third-Liquid Phase
- Reaction Rates and Surface Activities in a Liquid-Liquid Phase Transfer Catalyzed Reaction
- 相間轉移催化合成對-硝基苯丁基醚之研究
- 相間轉移催化1,1,1-三氯乙烷脫氯化氫反應之研究
- 二液相相間轉移催化反應之原理、發展及應用
- 液-固-液相間轉移催化反應
- 液-液相間轉移催化反應中誘導期之探討
- Reaction of Carbon Disulfide and O-Phenylene Diamine by Tertiary Amine in the Presence of Potassium Hydroxide
第1筆 /總和 1 筆
/ 1 筆
頁籤選單縮合
題 名 | 利用相間轉移觸媒合成對-羥基苯甲酸丁酯之研究=Studies on the Synthesis of N-Butyl P-Hydroxybenzoate Using Phase-Transfer Catalysis |
---|---|
作 者 | 王德優; 胡滌華; | 書刊名 | 技術學刊 |
卷 期 | 13:4 1998.12[民87.12] |
頁 次 | 頁593-600 |
分類號 | 460.02 |
關鍵詞 | 相間轉移催化反應; 對-羥基苯甲酸; 1-氯丁烷; 對-羥基苯甲酸丁酯; 四級銨鹽; 三級胺; Phase-transfer catalysis; P-hydroxybenzoic acid; 1-chlorobutane; N-butyl p-hydroxybenzoate; Quaternary ammonium salts; Tertiary amine; |
語 文 | 中文(Chinese) |
中文摘要 | 本研究以對--羥基苯甲酸和1--氯丁烷為原料,在鹼性條件下,以四級銨鹽為觸媒 進行相間轉移催化反應,以合成食品防腐劑對 -- 羥基苯甲酸丁酯。結果顯示反應的選擇性 會受到有機溶劑的影響,如使用甲苯、苯等不具有未共用電子對之有機溶劑,將無法生成對 -- 羥基苯甲酸丁酯,形成的多為雙取代產物,反之, 如使用具有未共用電子對之有機溶劑 ,如 1,4-- 二�x烷、甲乙酮、乙�舋央A則能如預期的生成對 -- 羥基苯甲酸丁酯。 研究中 亦發現,反應系統中所加入鹼的種類及用量對反應速率及選擇性均有影響,鹼性越強,反應 速率越快,鹼量與水相反應物對 -- 羥基苯甲酸用量相同時,能得到最高產率之對 -- 羥基 苯甲酸丁酯。此外研究中亦對觸媒種類及用量對反應的影響進行探討,結果發現在所使用之 四級銨鹽中,以碘化四丁基銨之催化效果最好,在本研究的實驗範圍內,反應會隨著碘化四 丁基銨用量的增加而加速進行。除了四級銨鹽外,研究中亦以三丁基胺催化反應的進行,雖 然三級胺之活性較差,但如配合碘化鈉之協催化效應,反應仍可以相當快之速率進行。 |
英文摘要 | In this study, n-Butyl p-hydroxybenzoate, an antimicrobial used in the food industry, was prepared by using phase-transfer catalysis of p-hydroxybenzoic acid and 1-chlorobutane. The synthetic reaction was catalyzed by quaternary ammonium salts in an alkaline solution. The results show that the selectivity of the reaction is influenced by the organic solvent. The disubstituted product can be obtained by using organic solvents without unshared electron pairs, such as toluene, benzene, etc. On the contrary, the reaction can proceed as expected to get desired product n-butyl p-hydroxybenzoate by using organic solvents with unshared electron pairs, such as 1,4-dioxane, MEK, acetonitrile, etc. The results also reveal that the selectivity and the rate of the reaction system are affected by the type and amount of base added to the system. The reaction with a strong base can proceed faster than that with a weak base. The maximum yield of n-butyl p-hydroxybenzoate can be obtained when the base amount is equal to that of p-hydroxybenzoic acid. In addition, different types and amounts of catalyst were selected to investigate their influences on the reaction. The results showed that tetrabutylammonium iodide exhibits the best catalytic activity among the quaternary ammonium salts used in this study. The reaction was accelerated by adding greater amounts of tetrabutylammonium iodide during the course of our experiment. Instead of quaternary ammonium salts, tributylamine was used as a catalyst to catalyze the reaction. Though the activity of the tertiary amine is poor, the reaction can proceed at a relatively faster rate by the addition of sodium iodide which acts as a cocatalytic agent in the reaction. |
本系統中英文摘要資訊取自各篇刊載內容。