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題名 | 先天性真皮黑色素細胞症--合併多發性藍痣樣病灶之一病例=Congenital Dermal Melanocytosis--A Case Combined with Multiple Blue Nevus-Like Lesions |
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作者 | 施宗賢; 陳佑甫; 洪志明; 蔡呈芳; | 書刊名 | 中華皮膚科醫學雜誌 |
卷期 | 16:2 1998.06[民87.06] |
頁次 | 頁113-118 |
分類號 | 415.687 |
關鍵詞 | 真皮黑色素細胞症; 太田氏母斑; 伊藤氏母斑; 藍痣; Dermal melanocytosis; Nevus of ota; Nevus of ito; Blue nevus; |
語文 | 中文(Chinese) |
中文摘要 | 真皮黑色素細胞症的特點為異位性的黑色素細胞出現在真皮層中,我們報告一特 殊的先天性真皮黑色素細胞症合併多發性藍痣樣病灶及白癜風(vitiligo)樣病灶,像這樣多 樣性的色素異常同時發生在一個人身上的病例在過去的英文文獻中尚未見過。 一位53歲的女性患者於出生時便在右手腕處出現一個棕色的斑塊,目前大小約10x8 cm,在 此斑塊中,並有一些顏色更深的小斑點。另外,自從她兒童時期便開始於四肢及臉部出現藍 黑色的小丘疹。取自右手腕斑駁斑塊及右前臂丘疹處之組織病理切片檢查發現二者均於真皮 層的上半部有著廣泛的黑色素細胞沉著,但是後者呈現更密集的黑色素細胞沉積,且呈腫瘤 樣分布。 |
英文摘要 | Dermal melanocytosis is characterzied by ectopic melanocytes present in the dermis. We report a case of congenital dermal melanocytosis combined with multiple bule nevus-like lesions and vitiligo-like lesions. Such case with complex pigment disorders has not been reported in English literature. A 53-year-old female presented with a brown patch with several darker macules within it on the right wrist since birth, size measured to 10 x 8 cm at present. In addition, many bluish black papules developed on her extremities and face since childhood. Both biopsy specimens taken from the speckled patchy lesion on the right wrist and papular lesion on the right forearm showed diffuse distribution of melanocytes in the upper dermis, but the melanocytes were distributed in a much more condensed manner and tumor-like pattern in the pattern in the papular lesion on the right forearm. |
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