頁籤選單縮合
題名 | Comparison of Detection of Extended-Spectrum β-Lactamases by Agar Dilution Method, E-Test ESBL Screen and Double Disk Test=比較瓊脂稀釋法、E-test ESBL篩選及雙藥紙錠試驗偵測廣效性β-lactamase之有效性 |
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作者 | 曾菁煜; 廖旭方; 吳婉玲; 劉有增; 胡伯賢; 施智源; 林育蕙; | 書刊名 | 微免與感染雜誌 |
卷期 | 31:2 1998.06[民87.06] |
頁次 | 頁90-94 |
分類號 | 419.38 |
關鍵詞 | 瓊脂稀釋法; E-test ESBL篩選; 雙藥紙錠試驗; Extended-spectrum β-lactamase; ESBL; Agar dilution method; E-test; Double disk test; |
語文 | 英文(English) |
中文摘要 | 廣效性β-lactamase(ESBL)是從TEM或SHV系列β-lactamase 演變而來。它們對廣 效性 betalactam 具抗藥性,並在醫院易造成感染之群突發。因此快速的確認及診斷對臨床 醫師是十分重要。本實驗根據 1993 年一月到 1997 年三月臺中榮總檢驗科細菌室報告顯示 對 cefotaxime, ceftazidime, ceftriaxone 或 aztreonam 為中等或高度抗藥性之克雷白 氏菌和大腸桿菌共 52 菌株,以傳統之瓊脂稀釋法為對照組, 比較 E-test ESBL 篩選及雙 藥紙錠試驗在偵測 ESBL 產生菌株上的準確性。 結果顯示 E-test ESBL 篩選及雙藥紙錠試 驗對傳統之瓊脂稀釋法的符合度為 86.5 %與 92.3 ∼ 100 %。 故兩者在偵測 ESBL 上, 均為有用且有效的方法。 |
英文摘要 | The extended-spectrum β-lactamases (ESBL) are derived from TEM-or SHV-enzymes. They mediate resistance to broad-spectrum β -lactams and can cause infectious outbreaks in hospitals. Rapid recognition and diagnosis are important for the clinician to prescribe more effective treatment. In the present study, a group of 52 probable ESBL-producing Klebsiella pneumoniae and Escherichia coli having a suspected resistant antibiogram phenotype were included. The E-test ESBL screen and the double disk test were performed for these isolates for detection of ESBL-producing strains, as compared with the conventional agar dilution method. The agreement between the E-test ESBL screen or the double disk test and the coventional agar dilution method was good and the degree of agreement were 86.5% and 92.3% respectively. The results showed that both the E-test ESBL screen and the double disk test were useful and convenient for detection of ESBLs. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。