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題名 | 接受手術以及手術後放射線治療的子宮內膜癌預後的分析=Prognosis of the Patients with Endometrial Adenocarcinoma after Surgical Staging Surgery and Postoperative Adjuvant Radiotherapy |
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作者 | 鄢源貴; 王鵬惠; 顏明賢; 趙灌中; 袁九重; 吳香達; Yen, Yuan-kuei; Wang, Peng-hui; Yen, Ming-shyen; Chao, Kuan-chong; Yuan, Chiou-chung; Ng, Heung-tat; |
期刊 | 中華民國婦癌醫學雜誌 |
出版日期 | 19980400 |
卷期 | 1998:1 1998.04[民87.04] |
頁次 | 頁30-36 |
分類號 | 417.27 |
語文 | chi |
關鍵詞 | 手術; 放射線治療; 子宮內膜癌; 預後; Endometrial adenocarcinoma of the uterus; Postoperative adjuvant therapy; Radiotherapy; Risk factors; Survival; |
中文摘要 | 目前有關子宮內膜腺癌的預後因子已經非常清楚了,然而大部份的研究則不限定 於術後有接受輔助性放射治療或沒有接受輔助性放射治療。雖然很多研究人員對此方面相當 有興趣,但目前子宮內膜癌術後加上輔助性放射的病人,我們對其預後及分析結果的所知仍 是不多。在本研究中,我們分析子宮內膜腺癌病人接受完整分期手術及術後輔助性放射治療 的重要預後因子。回顧臺北榮總婦產部自 1990 年至 1996 年的 29 個病例,根據病理方面 的報告及存活時間進行單獨變異性分析及多重變異性分析。在單獨變異性分析中發現骨盆淋 巴轉移,分期,癌細胞分化程度,子宮頸侵犯,子宮肌層超過一半都具有意義,但是在多重 變異性分析中,由於案例不多而致呈現不具意義的結果。總結來說在經過完整分期手術的子 宮內膜腺癌病人,同時帶有高危險因子,放射治療是最常採用的追加輔助性治療,但仍是有 病人的結果及預後不好,似乎我們必須考慮更有效的術後輔助治療,當然這更需要更多的研 究人員去尋找更好更有效的治療方式。 |
英文摘要 | Many prognostic factors have proposed to relate survival of the endometrial adenocarcinoma of the uterus; however, the majority of the data were based on the anlaysis of the patients with endometrial adenocarcinoma irrespective of having or not postoperative adjuvant radiotherapy. There is little knowledge to realize the outcome of the patients who had received thorough surgery followed postoperative adjuvant radiotherapy, although many investigators would be interested in knowing what were the results of the analyses. In this study, we analyze all the important factors of the patients with endometrial adenocarcinoma treated with combination of complete surgery and postoperative adjuvant radiotherapy. Twentynine patients were retrospectively (1990-1996) evaluated with their pathological aspects. Univariate and multivariate analyses of factors associated with survival were performed. Univariate analysis showed that pelvic lymph node metastasis, stage, differentiation grade of the cancer, myometrial invasion more than one half and cervix infiltrated were significant. However, multivariate anlaysis did not show significance due to only small amount of cases. We concluded that although the postoperative adjuvant radiotherapy is most commonly used in the patients with high-risk for their endometrial adenocarcinoma after completing surgical staging surgery, however, a more effective postoperative therapy would be required for such failed patients. Of course, it required more investigation to search for the more effective treatments. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。