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題 名 | Prevalence of Legionella Pneumophila Infection in Children and Its Role in Pediatric Community-Acquired Atypical Pneumonia=退伍軍人肺炎菌在臺灣兒童感染盛行率及兒童社區非典型肺炎之角色調查 |
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作 者 | 許峻銘; 黃立民; 高雲鳳; 計大偉; 李秉穎; 林逸甄; 張鑾英; 丘秀慧; 李慶雲; | 書刊名 | 中華民國小兒科醫學會雜誌 |
卷 期 | 37:3 民85.05-06 |
頁 次 | 頁188-192 |
分類號 | 417.5351 |
關鍵詞 | 退伍軍人肺炎菌; 兒童; 肺炎; Legionella pneumophila; Children; Atypical pneumonia; |
語 文 | 英文(English) |
中文摘要 | 退伍軍人肺炎菌在兒童感染情況及在兒童肺炎的角色一直不是很清楚。本研究利用血清抗體檢定來瞭解退伍軍人肺炎菌在台灣兒童疾病的重要性。由於缺一個血清抗體閥值以決定兒童是否曾感染過退伍軍人炎菌,我們首先測定60名12至18個月兒童血中退伍軍人肺炎菌抗體效價,這群兒童血清抗體值顯示螢光免疫抗體效價32可做爲是否曾感染退伍軍人肺炎菌的閥值。然後利用此閥值我們發現7至18歲兒童退伍軍人肺炎菌抗體陽性率介於28.4%至35%。此外爲瞭解退伍軍人肺炎菌在兒童非典型性肺炎的角色,我們收集53對來自非典型性肺炎病童血清,檢驗其抗體效價。53例非典型性肺炎中並無確定退伍軍人肺炎者,不過有3例(5.7%)疑似退伍軍人肺炎。因此我們認爲退伍軍人肺炎在台灣地區兒童肺炎中不常見。 |
英文摘要 | The infection status of Legionella pneumophila in children and its role in pediatric community-acquired pneumonia were investigated. Because exposure to Legionella pneumophila may be highly variable and there has been no unanimously agreed-upon cut-off values in previous seroprevalence studies, 60 serum samples collected from infants aged 12 to 18 months were examined using immunofluorescence antibody test to determine the cut-off titer which represents past Legionella pneumophila infection. An IFA titer of greater than or equal to 32 was found to be suitable to represent past L. pneumophila infection. A seroepidemiological study of the prevalence of L. pneumophila in 180 children showed the prevalences in children aged 7 to 18 years to be between 28.4 and 35%. Fifty-three paired sera were tested to determine the role of Legionella pneumophila in pediatric, community-acquired, atypical pneumonia. The frequency of confirmed disease was 0% and of presumptive cases was 5.7%. Legionella pneumophila was not a common etiologic agent of pediatric pneumonia in Taiwan. |
本系統中英文摘要資訊取自各篇刊載內容。