頁籤選單縮合
題名 | 醫療尖銳物品扎傷後人類免疫缺乏病毒和B型與C型肝炎病毒血清學之變化=Seroconversion Rate for Human Immunodeficiency, Hepatitis B and Hepatitis C Viruses After Sharp Medical Instrument Injury |
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作者 | 陳瑛瑛; 王永衛; 楊冠洋; 王復德; Chen, Yin-yin; Wong, Wing-wai; Yang, Guang-yang; Wang, Fu-der; |
期刊 | 院內感染控制雜誌 |
出版日期 | 19990800 |
卷期 | 9:4 1999.08[民88.08] |
頁次 | 頁183-193 |
分類號 | 419.38 |
語文 | chi |
關鍵詞 | 醫療人員; 扎傷; 血清陽轉; Health care workers; HCWS; Stick injury; Seroconversion; |
中文摘要 | 醫院員工被血液或體液污染的醫療尖銳物品扎傷後可能感染經血液傅播的致病微生物。本研究目的為瞭解醫院員工們(1)醫療尖銳物品扎傷之危險群分佈;(2)醫療尖銳物品扎傷後人數免疫缺乏病毒和B型與C型肝炎病毒之血清學變化。採世代追蹤研究法,以某醫學中心自83年7月4日到85年6月30日期間報告醫療尖銳物品扎傷之所有員工為研究對象,並定期追蹤扎傷後之血清學變化至86年6月30日止。本研究結果發現在2年期間所有員工的醫療尖銳物品扎傷共222件;護理人員的扎傷報告件數是非護理人量的2.45倍(95%信賴區間1.87-3.26,p<0.05),實習醫師的扎傷報告件數則是其他人員的1.61倍(95%信賴區間1.07-2.41,P<0.05);扎傷經常發生在套回針頭蓋子(37.896)及整理或清洗物品(13.1%);208(93.796)人次是被血液或體液污染的尖銳物品扎傷;在血清學方面,病患血清檢驗確知為anti-HIV陽性有2(0.9%)件,污染源確定HBsAg陽性反應共26(11.7%)件,有27人的B型肝炎抗原和抗體均呈陰性反應,致傷物品中10(4.5%)件確定遭受HCV污染,被扎傷者立即抽血檢驗anti-HCV呈陽性反應有4人;所有追蹤的扎傷報告者並未發現有H1V-HBV和HCV血清陽轉情形。 |
英文摘要 | Blood-borne pathogens could be transmitted by blood or body fluid-contaminated sharp medical instrment. The purpose of the present study was to ascertain the high-risk distribution in health-care workers (HCWs) who had sharp medical instrment injury, and the seroconversion rate among HCWs who sustained such injury. The study was processed by the cohort method. Starting from July, 1994 till June, 1996, all HCWs at a medical center who experienced the stick injuries were recruited and the serology for human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) followed up till June, 1997. During the 2-year study period, there were 222 episodes reported. The incidence for the nursing staff was 2.45 times that of non-nursing staff (95% confidence: 1.87-3.26; p<0.05), and the incidence for the medical interns was 1.61 times that of the others (95% confidence: 1.07-2.41; p<0.05). The stick injury occurred when HCWs were recapping the needles (37.8%) and cleaning medical vehicles (13.1%). In 208 episodes (93.7%), the sharp devises were contaminated by blood or body fluids. The devices were contaminated by HIV in two cases, HBV in 26, and HCV in 10. Four HCWs were found to have anti-HCV at the time of the injury. None of the injured seroconverted to any of the three viruses. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。