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頁籤選單縮合
題名 | Factors that Influence Spinal Bone Mineral Density in Postmenopausal Women=影響停經婦女脊椎骨密度之因素 |
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作者 | 陳芳萍; 鄧麗芬; 宋永魁; Chen, Fang-ping; Teng, Li-fen; Soong, Yung-kuei; |
期刊 | 中華民國婦產科醫學會會刊雜誌 |
出版日期 | 19971200 |
卷期 | 36:4 1997.12[民86.12] |
頁次 | 頁117-124 |
分類號 | 417.224 |
語文 | eng |
關鍵詞 | 脊椎骨密度; 身體質量指數; 荷爾蒙補充治療; Spinal bone mineral density; Body mass index; Hormone replacement therapy; |
中文摘要 | 目的:本研究在探討停經婦女脊椎骨密度與臨床各種因子的相關性。總共有149 位健康的停經婦女接受脊椎骨密度檢驗,並詳細檢視其臨床因子,包括:年齡,有關月經之因 子,有關生育因子,重量,身體質量指數,運動,及荷爾蒙補充治療合併鈣補充與否等。 結果:我們發現脊椎骨密度與年齡、停經年數及出現停經症候群之年齡呈有意義的關係, 但是與初經及停經之年齡無關。而在將其它因子加入調整後,只有停經年數及出現停經症候 群之年齡仍維持有意義的關係。在停經後的最初十年,脊椎骨密度比十年後的歲月呈有意義 的下降。運動和有關生育的因子對脊椎骨密度並無有意義的衝擊。雖然重量和身體質量指數 與脊椎骨密度之變化有關,但只有體重是有意義的指標。114位患者在接受荷爾蒙合併鈣補 充治療六個月後,脊椎骨密度呈有意義的上升。 結論:這些結果顯示:停經後雌激素的缺乏是影響脊椎骨密度變化之最重要因素。重量、 停經年數及出現停經症候群之年齡是影響脊椎骨密度有意義且獨立之因子。對停經婦女,尤 其是那些具有發展成骨質疏鬆症危險因子者,荷而蒙合併鈣補充治療應被儘早考慮使用。 |
英文摘要 | Objective: To evaluate the relationship between spinal bone mineral density (BMD) and the effects of clinical factors in postmenopausal women. Methods: We studied the spinal BMD of 149 healthy postmenopausal women. A detailed clinical history was taken, including age, menstrual history, reproductive factors, body weight, body mass index (BMI), exercise and hormone replacement therapy (HRT) with or without calcium supply. Results: Spinal BMD was found to be significantly related to age, years since menopause and age at development of present postmenopausal symptoms and signs, but it was not related to age at menarche and menopause. After adjustment for other variables, only years since menopause and age at development of present postmenopausal symptoms and signs remained significant. In the first 10 years after the onset of menopause, spinal BMD dropped more significantly than in subsequent years. The body weight and BMI both had a correlation with spinal BMD, but only body weight was a significant predictor of BMD. Exercise and reproductive factors did not have a significant impact on spinal BMD. Spinal BMD was significantly increased by 5% in 114 subjects receiving 6 months of HRT with calcium supplementation. Conclusions: These results indicated that estrogen deficiency after menopause was the most important factor related to spinal BMD. Body weight. years since menopause and age at development of present postmenopausal symptoms and signs were significant independent predictors of spinal BMD. HRT combined with calcium supplementation should be considered as early as possible in postmenopausal women, especially for those with risk factors for development of osteoporosis. |
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