頁籤選單縮合
題名 | A Randomized Clinical Trial Comparing a Collagen-based Composite Dressing versus Topical Antibiotic Ointment on Healing Full-thickness Skin Wounds to Promote Epithelialization= |
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作者 | Tsai, Hsin-chung; Shu, Hui-ching; Huang, Li-chuan; Chen, Chuan-mu; |
期刊 | Formosan Journal of Surgery |
出版日期 | 20190400 |
卷期 | 52:2 2019.04[民108.04] |
頁次 | 頁52-56 |
分類號 | 416.127 |
語文 | eng |
關鍵詞 | Acute traumatic wound; Composite dressing; Epithelialization; Ointment dressing; |
英文摘要 | Background: Acute traumatic wounds are a common and distressing event for patients presenting to plastic surgery clinics. There are no definitive conclusions regarding the benefits of collagen-based wound care products toward the application on full-thickness wounds compared to traditional ointment or gauze care. In this clinical trial, we aimed to define the potential benefits of collagen-based dressings on healing through the comparison of collagen-based composite dressings with antibiotic ointment dressings. Methods: This was a randomized two-tailed controlled clinical trial. The acute full-thickness wounds underwent wound cleansing, debridement, and were secured with different dressings in both experimental and control groups. The wounds were subsequently photographed weekly, and the wound areas were calculated using ImageJ software to evaluate wound healing rate. Results: The results demonstrate that the collagen-based triple layer composite dressings which consisted of silver sheet, collagen sponge, and foam films promoted better epithelialization and healing than antibiotic ointment treatment. Collagen supplementation improved wound healing and epithelialization by providing a dry environment during the late stage of wound healing. Conclusion: We demonstrated that the collagen-based triple layer wound dressing could potentially increase the healing rate when used for traumatic full-thickness wound care compared to the conventional antibiotic ointment dressing, providing a new prospective in the future applications of wound care. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。