查詢結果分析
來源資料
相關文獻
- 漫談幽門螺旋桿菌感染及基層醫療之對策
- New One-Week, Low-Dose Triple Therapy for the Treatment of Duodenal Ulcer with Helicobacter Pylori Infection
- A Multicenter Study on Eradication of Helicobacter pylori Infection in Patients with Duodenal Ulcer by Lansoprazole-Antibiotics Combined Therapy
- 消化性潰瘍的元兇--幽門螺旋桿菌
- 大黃抑制幽門螺旋桿菌及其作用機轉之研究
- 醇提大黃對消化性潰瘍合併幽門螺旋桿菌感染之作用探討
- 胃幽門螺旋桿菌的微生物學與流行病學
- 胃幽門螺旋桿菌與消化性疾病之因果關係
- 胃幽門螺旋桿菌的診斷與治療
- 胃幽門螺旋桿菌感染的未來展望
頁籤選單縮合
題名 | 幽門螺旋桿菌之治療=Tratment of Helicobacter Pylori Infection |
---|---|
作者 | 林政仁; 李建瑩; Lin, Zheng-ren; Lee, Chien-ying; |
期刊 | 藥學雜誌 |
出版日期 | 20161200 |
卷期 | 32:4=129 2016.12[民105.12] |
頁次 | 頁50-54 |
分類號 | 415.5 |
語文 | chi |
關鍵詞 | 幽門螺旋桿菌; Helicobacter pylori; Triple therapy; Sequential therapy; Quadruple therapy; High-dose dual therapy; |
中文摘要 | 目前治療幽門螺旋桿菌首選治療方法仍為質子幫浦阻斷劑 (Proton-pump inhibitors)、clarithromycin 和 amoxicillin (或 metronidazole) 所組成之標準三合一療法。 但近年來,隨著抗藥菌株的增加,幽門螺旋桿菌的滅菌成功率有下降之趨勢,因此有 許多新的療法被發展出來。目前,大部份治療準則仍是三合一療法為首選。但此一療 法在全球許多地區的失敗率高達20%以上。系列性治療是另一種第一線治療方法,其 滅菌成功率約84.3%,而高劑量 PPI 和 amoxicillin 組成之二合一療法不論在第一線或 第二線治療都有相當優異的表現,可能為將來在幽門螺旋桿菌的治療上另一個新的選 擇。在第二線治療上,以 PPI、鉍劑、tetracycline 和 metronidazole 所組成之四合一療 法或以 PPI、amoxicillin 和 levofloxacin 組成之三合一療法作第二線治療處方為主。 |
英文摘要 | Currently, the first-line therapy for Helicobacter pylori infection is standard triple therapy, consisting of a proton pump inhibitor, clarithromycin and amoxicillin. But in recent years, with the increase in drug- resistant strains of Helicobacter pylori sterilization success rate has declined the trend, so there are many new treatments being developed. Currently, most treatment guidelines triple therapy is still the first choice for Helicobacter pylori infection, but this treatment failure rates in many parts of the world up to 20%. Series of first-line therapy is another method of treatment, sterilization succes rate of 84.3%, while high-dose dual therapy and concomitant therapy have been developed and achieve a high eradication rate. The second-line therapy, most guidelines suggest a quadruple therapy. Recently, a triple therapy with the combination of a PPI, levofloxacin and amoxicillin and also achieve a high eradication rate. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。