頁籤選單縮合
題名 | Onychomycosis的藥物治療--醫學中心之回溯性評估=Pharmacotherapy of Onychomycosis--A Retrospective Assessment in a Medical Center |
---|---|
作者 | 黃宗賢; 陳麗芳; Huang, Tsung-hsien; Chen, Li-fang; |
期刊 | 藥學雜誌 |
出版日期 | 20120300 |
卷期 | 28:1=110 2012.03[民101.03] |
頁次 | 頁87-92 |
分類號 | 418.284 |
語文 | chi |
關鍵詞 | 甲黴菌病; Onychomycosis; Terbinafine; Itraconazole; Amorolfine; |
中文摘要 | 目前,甲黴菌病的治療以口服抗黴菌藥 (terbinafine 或 itraconazole) 為主。口服抗黴菌藥的治療方式,可分為 continuous therapy 及 pulse therapy 2種。研究顯示,terbinafine 的治療效果較 itraconazole 來得佳;而 continuous therapy 與 pulse therapy 2種治療方式,效果則無明顯的差異。至於外用抗黴菌藥物 amorolfine 主要用於輕微的甲黴菌病感染、不適合口服抗黴菌藥物的病人,或是與口服抗黴菌藥物合併治療。 針對某醫學中心之甲黴菌病病人進行回溯性評估:收集94-96年間完成12週口服抗黴菌藥 (terbinafine 或 itraconazole) 治療的病人,並追蹤病人於完成治療後21個月內之復發率。結果同樣顯示 terbinafine 組的復發率明顯低於 itraconazole 組 (0% vs 7.55%)。 |
英文摘要 | At present, the treatment of the onychomycosis is by taking oral medicine ( terbinafine or itraconazole ). Through taking orally, the modality can be divided into continuous therapy and pulse therapy. Clinical research showed the effect of terbinafine is better than itraconazole, and both continuous and pulse therapy are no obvious difference on the effect. Amorolfine is used for the mild onychomycosis, patient who is unsuitable to take antifungal drugs, or to combine with oral antifungals. We carried on the tracking back assessment to the onychomycosis patient in a medical center. During the year 2005-2007, collecting the patient that finished taking antifungals (either terbinafine or itraconazole) for 12 weeks, and assessed the relapse rate in 21 months after completing of treatment. The result showed that the relapse rate in terbinafine group is obviously lower than the itraconazole group (0% vs 7.55%). |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。