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題名 | Chronic Mucocutaneous Candidiasis in a 6-Year-Old Boy=一名六歲男孩羅患慢性皮膚黏膜念珠菌病 |
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作者 | 邱士榮; 曹景雄; 陳力振; 高俊傑; 呂克桓; 黃璟隆; Chiu, Shih-jung; Tsao, Ching-hsiung; Chen, Li-chen; Kao, Chun-chieh; Lue, Ko-huang; Huang, Jing-long; |
期刊 | 微免與感染雜誌 |
出版日期 | 20040600 |
卷期 | 37:3 2004.06[民93.06] |
頁次 | 頁196-199 |
分類號 | 415.725 |
語文 | eng |
關鍵詞 | 慢性皮膚黏膜念珠菌病; Case reports; Cellular immunity; Chronic mucocutaneous candidiasis; Diagnosis; |
英文摘要 | Chronic mucocutaneous candidiasis (CMC) is a complex disorder characterized by persistent or recurrent candidal infections of the skin, nails and/or mucous membranes. A familial occurrence has been reported in some instances, suggesting a genetic predisposition. CMC has also been suggested to be associated with a selective defect in T cell-mediated immunity to Candida antigens. Reports of cases in Asians are rare. We report a case of CMC in a 6-year-old boy with chronic candidal infection since 7 months of age. The patient presented with deficient cell-mediated immunity and decreased natural killer cells. This case highlights the need for detailed studies for evaluating the T-cell immunity in patients with chronic candial infection. |
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