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題名 | "T-shaped" Sign: A False-positive I-131 Uptake in the Sternum Mimicking Thyroid Cancer Metastasis=T型徵象:位於胸骨的偽陽性碘-131攝取擬似甲狀腺癌骨骼轉移 |
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作者 | 張雁翔; 王佩文; Chang, Yen-hsiang; Wang, Pei-wen; |
期刊 | Annals of Nuclear Medicine and Molecular Imaging |
出版日期 | 20130900 |
卷期 | 26:3 2013.09[民102.09] |
頁次 | 頁114-116+a15 |
語文 | eng |
關鍵詞 | 甲狀腺癌; 偽陽性; 碘-131掃描; 單光子放射斷層掃描; Thyroid cancer; False-positive; I-131 scan; SPECT/CT; |
中文摘要 | 一位罹患甲狀腺乳突癌的17歲女性病患在甲狀腺全切除術後接受碘-131治療(100毫居禮)。治療後造影呈現一個「T-型」放射活性位於胸骨。其促甲狀腺激素剌激下的血清甲狀腺球蛋白數値低。沒有局部疼痛,發炎徵象,或是外傷病史。後續的X-光檢查正常,門診追蹤亦無轉移的臨床徵象。這個位於胸骨的「T-型」放射活性被認爲是由於骨髓的碘-131攝取,爲一僞陽性的結果。這提醒我們對於瀰漫型且對稱的骨豁攝取,必須小心判讀,避免造成甲狀腺癌骨骼轉移的過度診斷。 |
英文摘要 | A 17-year-old female patient with papillary thyroid cancer received 1-131 therapy (100 mCi) after total thyroidectomy. The post-therapy scan revealed a “T-shaped” activity in the sternum. The TSH-stimulated serum thyroglobulin (Tg) level was low and the anti-Tg antibody (anti-Tg Ab) was negative. There was no local pain, no inflammatory sign, nor trauma history. Subsequent X-ray radiograph was normal and clinical sign showed no evidence of metastasis in out-patient follow-up. The “T-shaped” activity in the sternum was considered to be a false-positive finding, probably due to marrow uptake of 1-131. This reminds us that diffusely symmetric bone uptake, should be interpreted carefully to avoid an over-diagnosis of thyroid cancer bone metastasis. |
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