頁籤選單縮合
題名 | 疑似Flupentixol引起比薩症候群=Suspected Flupentixol-induced Pisa Syndrome |
---|---|
作者 | 盧令瑜; 鄭淑文; Lu, Ling-yu; Cheng, Shu-wen; |
期刊 | 藥學雜誌 |
出版日期 | 20130300 |
卷期 | 29:1=114 2013.03[民102.03] |
頁次 | 頁129-132 |
分類號 | 418.21 |
語文 | chi |
關鍵詞 | 比薩症候群; 肌張力障礙; Flupentixol; Pisa symdrome; Pleurothotonus; |
中文摘要 | 比薩症候群 (pisa syndrome,簡稱PS) 為一種罕見的急性或遲發性肌張力障礙 (pleurothotonus),病人在服用精神科藥品時,由於 dopamine 路徑影響,引起類似錐體外徑症候群 (extrapyramidal symptoms),呈現「比薩斜塔」之型態而稱之1。本篇為一長期單獨使用 flupentixol 治療之個案發生比薩症候群之案例報告。雖然在治療上尚未被確立其治療準則,但精神科藥品在治療上應使用最低有效劑量並密切監測病人之反應以防止不良反應的發生。 |
英文摘要 | Pisa syndrome (or pleurothotonus) is a rare adverse drug reaction seen in patients who are taking long-term antipsychotics. Pisa syndrome is characterized by a body involuntary sustained lateral flexion with the head to one side, creating a "leaning tower" posture due to the influence of the drug on dopaminergic pathways. This was a ADR case of Pisa syndrome caused by long-term use of flupentixol. Although diagnosis has not been established, treatment with antipsychotics would start at a lower affinity and lower effective dosage. Therefore, clinical response of patients who receive medical therapy should be monitored carefully so that the risk of drug-induced adverse reaction can be reduced if necessary. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。