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題名 | Choroid Metastasis from Primary Lung Cancer in 26-year-old Male Successfully Treated with Pemetrexed--Case Report and Literature Review=在一位26歲肺癌患者合併眼球脈絡膜轉移,成功使用Pemetrexed治療--案例報告及文獻回顧 |
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作者 | 張維安; 楊志仁; 李柏延; 黃吉志; 鍾飲文; 黃明賢; Chang, Wei-an; Yang, Chih-jen; Lee, Po-yen; Huang, Jhi-jhu; Chong, Inn-wen; Huang, Ming-shyan; |
期刊 | 胸腔醫學 |
出版日期 | 20120600 |
卷期 | 27:3 2012.06[民101.06] |
頁次 | 頁159-166 |
分類號 | 415.468 |
語文 | eng |
關鍵詞 | 脈絡膜轉移; 肺癌; 愛寧達; Choroid metastasis; Lung cancer; Pemetrexed; |
中文摘要 | 肺癌合併眼球脈絡膜轉移被認為是較差預後的象徵。針對眼球脈絡膜轉移的第一線治療方法為放射線治療,但可能會併發視力缺損甚至於全盲,另外也可以使用手術、雷射以及化學治療。化學治療並非廣泛使用,回顧之前的文獻,尚無以Pemetrexed成功治療肺癌合併眼球脈絡膜的報告。這位26歲男性被診斷為肺腺癌,經過化學治療之後疾病仍持續進展並出現新的眼力模糊,經過一系列眼科檢查,發現是罕見的眼球脈絡膜轉移,推測是轉移自原本的肺腺癌。經過Pemetrexed的治療之後,病人的視力完全回復,且眼底檢查也顯示眼球脈絡膜轉移癌完全消散。就我們所知,這是第一個肺癌合併眼球脈絡膜轉移且成功地以Pemetrexed治療的病人,我們分享此經驗並作文獻回顧。 |
英文摘要 | Choroid metastasis from primary lung cancer is rare and has a poor prognosis. It can be treated with an external beam of radiation or by laser photocoagulation. However, visual defects or blindness are possible complications related to radiotherapy. Chemotherapy for such a condition has not been widely reported. We report a 26-year-old patient who had stage IV lung adenocarcinoma and suffered from progressive blurred vision during a scheduled chemotherapy regimen. Fundoscopy, fluorescence angiography and optic coherence tomography indicated choroidal metastasis of both eyes. We prescribed a platinum double chemotherapy regimen with pemetrexed and cisplatin. A follow-up examination demonstrated complete remission of the choroid metastasis. Herein, we report the first case of lung cancer with choroid metastasis that underwent complete remission after pemetrexed administration. We share our experience and conduct a literature review. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。