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頁籤選單縮合
題名 | Sun Protection Factor Analysis of Sunscreens Containing Titanium Dioxide Nanoparticles=化粧品含奈米級二氧化鈦之防曬係數研究 |
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作者 | 林澄琴; 林文貞; Lin, Cheng-chin; Lin, Wen-jen; |
期刊 | Journal of Food and Drug Analysis |
出版日期 | 20110300 |
卷期 | 19:1 2011.03[民100.03] |
頁次 | 頁1-8+103 |
分類號 | 466.7 |
語文 | eng |
關鍵詞 | 防曬係數; 奈米級二氧化鈦; 次微米級二氧化鈦; Sun protection factor; SPF; Nanosized TiO2; Submicron TiO2; |
英文摘要 | ABSTRACT The effect of micronization on sun protection factor (SPF) were tested on two types of titanium dioxide (TiO2) with primary particle sizes of 20 nm and 170 nm. Oil/water creams with 5%, 10%, and 20% concentrations of each type of TiO2 were prepared, and SPF was measured using both in vitro and in vivo methods. In vitro analysis demonstrated that submicron-sized TiO2 cream had a lower SPF value than nanosized TiO2 formulations of the same concentration. In vivo experiments confirmed this result, and a strong correlation between in vitro and in vivo measurements was observed. Furthermore, the SPF values of nanosized TiO2 sunscreen were concentration-dependent in the range of 5% to 20%. Scanning electron microscopy results indicate that the higher SPF of nanosized TiO2 formulations may be due to the formation of multilayer agglomerates by small particles at nano-scales, leading to a reduced void space between particles and a more efficient barrier to protect skin from sunlight. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。