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頁籤選單縮合
題名 | Kimura Disease: A Case Report and Literature Review=木村氏病:案例報告和討論 |
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作者 | 張瓊方; 陳信翰; 吳肇毅; 許永昌; 張家寧; | 書刊名 | 臺灣整形外科醫學會雜誌 |
卷期 | 20:3 2011.09[民100.09] |
頁次 | 頁236-242 |
分類號 | 416.21 |
關鍵詞 | 木村氏病; 頭頸部; Kimura disease; Eosinophilia; Hyperplasia of germinal centers; |
語文 | 英文(English) |
中文摘要 | 背景:木村氏病是一種好發於東方中年男性的罕見疾病,由於此病的表徵並沒有專一性,所以不容易診斷,通常是在頭頸區域呈現無痛性的腫脹,病人大多是爲了美觀來尋求整形外科的幫忙。目的及目標:由於木村氏病十分罕見,因此我們從蒐集到的文獻之中整理出木村氏症的相關資料,包括流行病學,常見的症狀,診斷工具,病理切片以及治療方法,做個完整的回顧。材料及方法:在這篇論文中,我們介紹了一個比較特殊的案例,一位外籍新娘因爲左頭皮腫脹合併壓痛的表現前來就診,其血液生化檢查並無嗜酸性白血球的異常,同時也無腎功能的缺損。結果:此病人之腫塊在我們以手術切除之後,病理切片顯示木村氏症的專一表現,因此木村氏症診斷確立,同時,病人之左頭皮腫脹合併壓痛的症狀也隨之消失,追蹤了兩年仍無復發的現象。結論:雖然木村氏病是一種病理診斷的疾病,我們仍然可以從血液生化檢驗或是影像學診斷中追尋到一些蛛絲馬跡。而目前爲止,手術介入移除腫塊仍是治療上的第一選擇。 |
英文摘要 | Background:Kimura disease (KD) is a chronic and benign inflammatory disease and the etiology is still unknown. KD is rare and primarily seen in young Asian males. It is usually presented as painless subcutaneous masses or regional lymphadenopathy over head and neck. Patients with KD may be transferred from other departments for cosmetic need with diverse non-specific complaints. For diagnostic imaging, ultrasonography and magnetic resonance imaging (MRI) reveal more characteristic findings than computed tomography (CT). However, histopathology is the most convincible method to prove the disease.Aim and objectives:We presented a patient with a tender palpable mass over posterior scalp from clinical symptoms, laboratory data, and images to the pathological findings and reviewed the details of KD from the literature.Materials and Methods:In this paper, we reported one female patient with KD which presented a tender palpable mass over posterior scalp. Her peripheral blood data including eosinophils count and renal function were normal.Results:The mass was excised completely and histopathological investigation revealed hyperplasia of germinal centers accompanied with capillaries proliferation and rich eosinophils infiltration. Thus KD was diagnosed according to the result of histopathology. The local tenderness subsided after the mass removal. The patient was regularly followed up for 2 years without recurrent symptoms.Conclusion:Although KD is a pathological diagnosed disease, we could still find some clues by blood laboratory data and image study. Surgery is the first choice of therapy, while other conservative management such as regional or systemic corticosteroid therapy, radiotherapy and medication therapy has also been reported. Although KD has a high recurrence rate, it is definitely a benign disease which must be differentiated from malignant neoplasms. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。