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題 名 | 幼年型卵巢顆粒細胞瘤=Juvenile Granulosa Cell Tumor of the Ovary |
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作 者 | 李耀泰; 陳福民; 郭宗正; | 書刊名 | Medical Journal of South Taiwan |
卷 期 | 7:1 2011.06[民100.06] |
頁 次 | 頁59-63 |
分類號 | 417.25 |
關鍵詞 | 幼年型卵巢顆粒細胞瘤; 卵巢癌; Juvenile granulosa cell tumor; Ovarian cancer; |
語 文 | 中文(Chinese) |
中文摘要 | 幼年型卵巢顆粒細胞瘤為卵巢顆粒細胞瘤的一亞型,多發生在30歲以前的女性,並常會有性早熟的徵兆。在組織病理學上,幼年型顆粒腫瘤之細胞呈瀰漫型或巨大濾泡型、細胞核濃染、形狀不一、缺乏核溝、分裂多,但少見Call-Exner小體。由於幼年型卵巢顆粒細胞瘤發現時多屬一期初,在排除高危險預後因子, 及有生育考量,小於40歲的病人,行單側輸卵管卵巢切除效果即很好。但晚期病灶之復發率和死亡率仍高,建議宜長期追蹤。 |
英文摘要 | The juvenile granulosa cell tumor is a histologic subtype of ovarian granulosa cell tumor occurring most frequently in the first three decades of life. Patients with juvenile granulosa cell tumors often present with isosexual precocity. Histopathologic examination of juvenile granulosa cell tumor reveals a number of characteristics, including diffuse and macrofollicular patterns, round hyperchromatic pleomorphic nuclei, absent nuclear grooves, high mitotic rate, and rare or absent Call-Exner bodies. Most juvenile cell tumors are diagnosed in stage Ia and can be cured by unilateral salpingo-oophorectomy alone. The follow-up data indicate a high cure rate of the juvenile granulosa cell tumor. However, it is aggressive in advanced stages, and the time to relapse and death is of short duration than adult granulose cell tumors, prolonged surveillance is required. |
本系統中英文摘要資訊取自各篇刊載內容。