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題名 | Surgical Management for Stage, I, II Anorectal Melanoma : an Experience of a Single Institution=第一及第二期肛門直腸黑色素瘤之手術治療:單一醫療機構之經驗 |
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作者 | 蔣昇甫; 陳進勛; 張簡俊榮; 唐瑞平; 游耀東; 江支銘; 謝寶秀; 葉建裕; 蔡文司; | 書刊名 | 臺灣外科醫學會雜誌 |
卷期 | 41:5 2008.09-10[民97.09-10] |
頁次 | 頁209-216 |
分類號 | 416.245 |
關鍵詞 | 肛門直腸黑色素瘤; 腹部會陰切除術; Anorectal melanoma; Abdominoperineal resection; Local excision; Tumor size; |
語文 | 英文(English) |
中文摘要 | 肛門直腸黑色素瘤是罕見且預後極差之腫瘤,其手術治療仍具爭議性,本文之目的是在探討,對於第一及第二期肛門直腸黑色素瘤,腹部會陰切除術(APR, abdominoperineal resection)是否較局部切除(local excision)爲佳。本研究回溯追蹤從1976年至2007年間,於林口長庚醫院接受手術治療之16位肛門直腸黑色素瘤患者,其中10位爲第一期或第二期之病患,我們比較其手術方法與預後。我們發現第一期之肛門直腸黑色素瘤患者之預後,較第二期之患者爲佳,且對於早期可切除之肛門直腸黑色素瘤(第一期、腫瘤較小、侵犯深度較淺、腫瘤厚度較薄),腹部會陰切除術是較佳之手術選擇。我們認爲第一期之肛門直腸黑色素瘤,伴隨腫瘤小於2 cm、侵犯深度不超過黏膜下層、腫瘤厚度小於8 mm者,仍應以腹部會陰切除術(APR)作爲根除性之于術。 |
英文摘要 | Objective: The aim of our study was to determine whether APR (abdominoperineal resection) was the better choice for stage Ⅰ and stage Ⅱ anorectal melanoma. Methods: A retrospective study of 16 patients from Chang Gung Memorial Hospital between 1976 and 2007 was made. Ten of them had stage Ⅰ and stage Ⅱ diseases. We analyzed their surgical methods and outcomes. Results: Stage Ⅰ patients had a better outcome than stage Ⅱ patients. APR was the preferred curative surgical method for anorectal melanoma (stage Ⅰ, smaller tumor size, shallower invasion depth, and thinner tumor thickness). Conclusions: We recommend APR as curative surgery for stage Ⅰ anorectal melanoma with tumor size of less than 2 cm, tumor invasion depth not surpassing the submucosal layer, and tumor thickness of less than 8 mm. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。