查詢結果分析
來源資料
相關文獻
- Clinical Features and Prognostic Factors of Lung Abscess
- Prognostic Factors in Node-Negative Breast Cancer Patients: The Experience in Taiwan
- Postoperative Radiotherapy of Adult Supratentorial High-grade Astrocytoma
- 成人低惡性度顱內星狀細胞瘤之術後放射治療
- Detection of Serum Anti-p53 Antibody in Patients with Renal Cell Carcinoma
- 擬身體障礙症之臨床特徵
- 乳癌預後因子探討--論流式細胞分析儀在乳癌之應用
- Prognostic Factors and Results of Radiotherapy for Brain Stem Gliomas
- Prognostic Value of DNA Ploidy Patterns of Colorectal Adenocarcinoma
- Salmonella Lung Abscess and Empyema in a Patient with Metastatic Papillary Thyroid Carcinoma--A Case Report
頁籤選單縮合
題名 | Clinical Features and Prognostic Factors of Lung Abscess=肺膿瘍臨床表現暨預後因子之探討 |
---|---|
作者 | 鄭任勳; 陳炯睿; 朱遠志; 李政宏; 陳昌文; 張漢煜; 薛尊仁; Cheng, Jen-hsun; Chen, Chiung-zuei; Chu, Yuan-chih; Lee, Cheng-hung; Chen, Chang-wen; Chang, Han-yu; Hsiue, Tzuen-ren; |
期刊 | 胸腔醫學 |
出版日期 | 20041200 |
卷期 | 19:6 2004.12[民93.12] |
頁次 | 頁445-452 |
分類號 | 415.464 |
語文 | eng |
關鍵詞 | 肺膿瘍; 臨床特徵; 預後因子; Lung abscess; Clinical feature; Prognostic factor; |
中文摘要 | 背景:雖然在過去的幾年對於病人之醫療照顧有明顯的進步,肺膿瘍仍然持續有相當高的死亡率。本研究旨在探討肺膿瘍臨床表現暨預後因子。 方法:我們回溯性之研究分析從1997年一月至2003年十二月總計六年期間,在成功大學附設醫院診斷為肺膿瘍並接受治療之病人的病歷記錄與放射學檔案。 結果:在這段研究的時間總計有五十位罹患肺膿瘍之病人。平均年齡是61歲(範圍由22到88歲)。平均住院天數為23.6±13.9天。8位病人死亡,死亡率為16%。肺膿瘍患者常合併之危險因子依序是吸煙(48%)與糖尿病(34%)。引起肺膿瘍細菌方面的分析Klebsiella pneumoniae是最主要的病菌(5/15, 33%)。至於預後因子之分析,到院時貧血(血色素<12gm/dl)的患者有較高的死亡率分別為29.7% vs 0%(p=0.005)。死亡患者比起存活患者經治療後有較長的發燒期間分別是13.9±7.5 vs. 5.6±4.4天(p=0.001)。經抗生素治療,仍然發燒超過七天是一個不好的預後因子,其死亡率分別是35% vs. 3%(p<0.05)。 結論:即使是抗生素治療的進步,肺膿瘍死亡依舊相當的高。到院時貧血與在廣效抗生素治療下持續性高燒大於七天是影響肺膿瘍患者死亡之兩個重要的危險因子。 |
英文摘要 | Background and purpose: Despite the advances in the care of patients with lung abscess during the past few years, lung abscess continues to cause significant morbidity and death. In order to increase understanding of this condition, this study was designed to assess the clinical features and prognostic factors of lung abscess. Methods: We retrospectively reviewed the medical records and chest radiographs of adult inpatients with lung abscess, who were treated at the National Cheng Kung University Hospital from January 1997 through December 2003. Results: A total of 50 patients with lung abscesses were evaluated during the study period; the median age was 61 years old (range, 22 to 88 years). The mean hospital stay was 23.6±13.9 days (range, 8-80 days). Eight patients died, yielding a mortality rate of 16%. The risk factors for lung abscess included smoking (48%) and diabetes mellitus (34%), followed by lung cancer (16%). Klebsiella pneumoniae was the major pathogen found in this study (5/15, 33%). Patients who died had significantly lower hemoglobin levels than those who survived (10.8±1.6 g/dl vs. 12.3±2.0 g/dl, p<0.05). As we chose a hemoglobin level of 12 g/dL as the cut-off point, the patients with anemia on admission had a higher mortality rate than those without (8 of 27 vs. 0 of 23, p=0.005). The patients who died had a longer duration of fever after treatment began than those who survived (13.9±7.5 days vs. 5.6±4.4 days, p=0.001). Patients with fever lasting more than 7 days after the beginning of antibiotic treatment had a poor prognosis and were associated with a higher mortality rate than those with fever lasting less than 7 days (35% vs. 3%, p<0.05). Conclusions: A high rate of morbidity and mortality is associated with lung abscess despite the advances in antibiotic treatment. Anemia and prolonged fever after the beginning of antibiotic treatment were 2 risk factors that affected the mortality rate in patients with lung abscess. |
本系統之摘要資訊系依該期刊論文摘要之資訊為主。